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                    John Gay, DVM PhD DACVPM               AAHP                  FDIU             VCS


Vet Clin 576 - Introduction to Clinical Research

Veterinary Clinical Research Links & Resources

Ver. 3.1   Initial 9/05/06 Updated 09/18/14


The purpose of this web page is to provide links to on-line resources for clinical research and EBVM. I update this list irregularly as I happen onto good on-line resources and when I need to use it for teaching.  Please let me know if you find broken links, mistakes or resources that I've overlooked.


Ceteris paribus "with all other things being the same" (wikipedia latin phrases)

Contents:


Current Class Information:

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Recommended Books:

(Note: The Amazon links are provided for your convenience, not as a recommended source)

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WSU Specific Resources:

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DOE - Experimental and Observational Study Design, Design of Experiments:

Without good experimental design, we often end up doing PARC analysis (Planning After the Research is Complete) - (hint: invert) - Stu Hunter per Econotec pdf

  • A Field Guide to Experimental Designs (WSU Tree Fruit Research and Extension Center)
  • ASHP Foundation (American Society of Health-System Pharmacists) - Research Resources
    • Building upon existing evidence to shape future research endeavors (KM Smith, Am J Health-Sys Pharm 65(18):1767-1774, 2008) - html  pdf
    • Developing great research questions (EE Lipowski, Am J Health-Sys Pharm 65(17):1667-1670, 2008) - html pdf
      • Comparative effectiveness research: Relevance and applications to pharmacy (GT Schumock, AS Pickard, Am J Health-Sys Pharm 66(4):1278-1286, 2009) - html  pdf
      • The design of randomized clinical trials in critically ill patients (Herbert PC et al. Chest 121(4:1290-1300, 2002) - html  pdf
    • Developing and executing an effective research plan (RJ Weber, DJ Cobaugh, Am J Health-Sys Pharm 65(21):2058-2065, 2008) - html  pdf
    • Validity and reliability of measurement instruments used in research (CL Kimberling, AG Winterstein, Am J Health-Sys Pharm 65(23):2276-2284, 2008) - html  pdf
    • Bias: Considerations for research practice (T Gerhard, Am J Health-Sys Pharm 65(23):2519-2168, 2008) - html  pdf
    • Overview of biostatistics used in clinical research  (JE De Muth, Am J Health-Sys Pharm 66(1):70 - 81, 2009) - html  pdf
    • Preparing for the first meeting with a statistician (JE De Muth, Am J Health-Sys Pharm 66(1):70 - 81, 2009) - html  pdf
    • Overview of clinical research design (DM Hartung, D Touchette, Am J Health-Sys Pharm 66(4):398-408, 2009) - html  pdf
    • The art of obtaining grants (EB Devine, Am J Health-Sys Pharm 66(6):580-587, 2009) - html  pdf
    • presenting:
      • The 10-minute oral presentation: What should I focus on? (CA Estrada et al. Am J Med Sci 329(6):306-309, 2005)
      • Fundamentals of surgical research course: research presentations (K Mayer, J Surg Res 128(2):174-177, 2005)
    • Preparing manuscripts for submission to medical journals: The paper trail (HG Welch, Effective Clinical Practice, May/June 1999) - html
  • Chemometrics
    • Introduction to Statistical Experimental Design - What is it? Why and Where is it Useful? (J Trygg, S Wold) - abstract
  • Communicating Design of Experiments (DOE) to Non-statisticians (S Schmidt, K Case, Air Academy Associates)
  • Concepts Underlying the Design of Experiments (pdf - U Reading Statistical Services Center Good Practice Guides)
  • Curious Cat - guides
  • Dallal, GE - The Little Handbook of Statistical Practice
  • Design of Comparative Experiments, on-line text draft (RA Bailey)
  • Design of Experiments - Basic Concepts (Improvement and Innovation.com)
  • DesignTheory.org
  • Design of Experiments (DOE) (More Steam.com Six Sigma toolbox)
  • Dillman - papers
    • survey example (at end of paper) - pdf
    • bknotes - pdf
  • EMGO - Institute for Health and Care Research
  • Equator network: Enhancing the QUAlity and Transparency Of health research
  • Experiment-resources
  • FDA - Drug Study Designs
    • Drug Interaction Studies - Study design, data analysis, implications for dosing, and labeling recommendations - pdf
  • ILAR Journal  43(4), 2002 (Institute for Laboratory Animal Research) Experimental Design and Statistics in Biomedical Research
    • The Design and Statistical Analysis of Animal Experiments (ILAR J 43(4):191-193, 2002 html pdf)
    • Control of Variability (ILAR J 43(4):194-201, 2002 html pdf)
    • Practical Aspects of Experimental Design in Animal Research (ILAR J 43(4):202-206, 2002 html pdf)
    • Sample Size Determination (ILAR J 43(4):207-213, 2002 html pdf)
    • Role of Ancillary Variables in the Design, Analysis, and Interpretation of Animal Experiments (ILAR J 43(4):214-222, 2002 html pdf)
    • Use of Factorial Designs to Optimize Animal Experiments and Reduce Animal Use (ILAR J 43(4):223-232, 2002 html  pdf)
    • Guidelines for the Design and Statistical Analysis of Experiments Using Laboratory Animals (ILAR J 43(4):244-258, 2002 html pdf)
  • Ishikawa Fishbone (cause-and-effect) diagrams - wiki
    • Ishikawa Variance Diagram (mine) - jpeg  pdf
  • Isogenic (Michael FW Festing) - design and statistical analysis of experiments involving laboratory animals
  • NIST Engineering Statistics Handbook
  • Environments to Experiment
    • Virtual Experiments and their Role in Teaching Design and Analysis of Experiments (pdf)
    • Using web-based tools for teaching statistical concepts and experimentation skills (pdf)
    • Use of virtual experiments in teaching design and analysis of experiments (pdf)
  • Latin square designs
  • Optimum Experimental Design (down?)
  • PaT Plot - Randomized controlled trial design tool
  • Practical tips for surgical research - Canadian Journal of Surgery
    • Introduction to the series, Farrokhyar F, M Bhandari Can J Surg 53(1):67-68 (2010) - pdf
    • Ethical issues in surgical research, McDonald PJ et al. Can J Surg 53(2):133-136 (2010) - pdf
    • How to optimize patient recruitment, Thoma A Can J Surg 53(3):205-210 (2010) - pdf
    • Research questions, hypothesis, and objectives, Farrugia P et al.  Can J Surg 53(4):278-281 (2010) - pdf
    • Blinding: Who, what, when, why, how? Karanicolas PJ et al.  Can J Surg 53(5):345-348 (2010) - pdf
    • Ensuring balanced groups in surgical trials, Farrokhyar F, et al Can J Surg 53(6):418-423 (2010) - pdf
    • Why perform a priori sample size calculation? Farrokhyar F, et al Can J Surg 56(3):207-213 (2013) - pdf
  • Research Design Review - WB King, Coastal Carolina U
  • Research Methods Knowledge Base - WMK Trochim, Cornell
  • The Basics of Experimental Design [A quick and non-technical guide] (Sid Sytsma on RM Mottola's Lutherie Information Website)
  • The rationale of scientific experimentation (JS Dowd pdf)
  • TRESS - The Really Easy Statistics Site (J Deacon, U Edinburgh, archived)
  • Warning signs in experimental design and interpretation (Peter Norvig, Google Director of Research)
  • Research reporting guidelines and initiative by organization - NIH NLM
  • WHO
    • Health Research Methodology: A guide for training in research methods, 2nd ed 2001 - pdf
  • standards for reporting  & consensus statements - examples:
    • ARRIVE Guidelines - Animal Research: Reporting In Vivo Experiments - NC3RS - PLOS paper
    • CONSORT - Consolidated standards of reporting trials
    • GRADE - Grading of recommendations, assessment, development, and evaluation - systematic reviews, clinical practice guidelines
    • MIBBI - Minimum information guidelines from diverse bioscience communities
      • MIFlowCyt - Minimum information about a flow cytometry experiment
    • MOOSE - Meta-analysis of observational studies in epidemiology
    • PRISMA - Preferred reporting items for systematic reviews and meta-analyses
    • REFLECT - Reporting guidelines for randomized controlled trials for livestock and food safety
    • STARD - Standards for the reporting of diagnostic accuracy studies
    • STROBE - Strengthening the reporting of observational studies in epidemiology
  • standards for laboratory methods, protocols, and materials - examples:
    • AOAC International - Association of Analytical Communities - development, use, and harmonization of validated analytical methods
    • ASVCP Principles of quality assurance and standards for veterinary clinical pathology - index
    • ATCC - preservation, development and distribution of standard reference microorganisms, cell lines and other materials
    • CLSI - Clinical and Laboratory Standards Institute
    • OIE Manual of Diagnostic Tests and Vaccines for Terrestrial Animals   Aquatic Animals
    • Protocolmonkey: Your friendly laboratory research assistant
    • Springer Protocols - subscription-based database of reproducible, step-by-step, recipe-style laboratory protocols for the biomedical sciences
    • method validation:
      • FDA – Bioanalytical method validation, 2001 - pdf
      • EEC – Guideline on bioanalytical method validation, 2011 - pdf
      • OIE - Principles and methods of validation of diagnostic assays for infectious diseases, 2009 - pdf
    • technique-specific:
    • books:
      • Freifelder, D (1982). Physical Biochemistry: Applications to biochemistry and molecular biology, 2nd ed - (dated but valuable source of information on physical and chemical principles behind centrifugation, pH, fluorescence, filtration, electrophoresis, microscopy and so on)
        • More recent but less applied equivalents may be Davidovitis "Physics in Biology and Medicine" 3rd ed, Hobbie & Roth "Intermediate Physics for Medicine and Biology" 4th ed, and Newman "Physics of the Life Sciences."
      • Oxford Press IRL Practical Approach Series
        • Ex: Preparative Centrifugation: A practical approach
  • software:
    • EDGAR - Experimental Design Generator and Randomizer
    • Design of Experiments Website (constructs block designs, factorial designs, nested block designs, and so on on-line - dead?)
  • papers:
    • A decision making checklist for animal nutrition studies in livestock development - pdf
    • A decision tree for controlled trials (Batterham AM, WG Hopkins Sportscinece 9:33-39, 2005) - pdf
    • A Gold Standard Publication Checklist to improve the quality of animal studies, to fully integrate the three Rs, and to make systematic reviews more feasible (Hooijmans CR, M Leenaars, M Ritskes-Hoitinga ATLA: Alternatives to Lab Animals 38(2):167-182. 2010) - pdf
    • Common statistical errors in the design and analysis of subfertility trials (A Vail, E Gardener, Human Reproduction 18(5):1000-1004, 2003) html  pdf
    • Designing studies that answer questions (S Shott, JAVMA 238(1):55-58, 2011) - pdf
    • Evaluation of diagnostic tests for infectious diseases: General principles (Banoo S, D Bell, P Bossuyt et al. Nature Rev Microb 8(12):S16-S28  - pdf  html
    • Enhancing search efficiency by means of a search filter for finding all studies on animal experimentation in PubMed (Hooijmans CR et al. Laboratory Animals 44(3):170-175, 2010) - DOI: 10.1258/la.2010.009117
    • Evidence-based radiology: Step 1 - Ask (A Kelly, Sem Roentgenology 44(3):140-146, 2009)
    • Illustrating degrees of freedom in terms of sample size and dimensionality  (C H Yu)
    • Logic of experiments in ecology: Is pseudoreplication a pseudoissue? (L Oksanen, OIKOS 94: 27–38, 2001) - pdf
    • Improved experimental design and analysis for long-term experiments (T Loughin Crop Sci 46:2492–2502, 2006) - pdf
    • Pitfalls in the design and analysis of efficacy trials in subfertility (S Daya, Human Reproduction 18(5):1005-1009, 2003) - html  pdf
    • Poor-quality medical research: What can journals do? (DG Altman, JAMA 287(21):2765-2767, 2002)  html  pdf
    • Reading the literature and developing a hypothesis (GB Nackman, J Surg Res 128(2):158-161, 2005)
    • Remedies for pseudoreplication (RB Millar, MJ Anderson, Fisheries Res 70:397-407, 2004) - pdf
    • Selected statistical issues in group randomized trials (Z Feng et al. Ann Rev Public Health 22:167-187, 2001) - pdf
    • Some experimental design and statistical criteria for analysis of studies in manuscripts submitted for consideration for publication (Anon, Animal Feed Sci Techn 129:1-11, 2006) - pdf
    • * Understanding and evaluating veterinary clinical research (W Buhles, PH Kass, J Am Anim Hosp Assoc 48: , 2012) - pdf
    • Viewpoint: Replication, randomization, and statistics in range research (DB Wester, J Range Manage 45(3):285-290, 1992) - pdf  pdf2
    • What are degrees of freedom?, 1973 (IJ Good, The American Statistician 27(5):227-228) - pdf
  • books:
    • Biological Variation: From principles to practice, (CG Fraser, 2001) - Amazon
    • Design and Analysis of Experiments, 7th ed (DC Montgomery, 2009) - Amazon
    • Design of Experiments for Engineers and Scientists, (J Antony, 2003) - Amazon
    • Experimental Design for the Life Sciences, 3rd ed. (GD Ruxton, N Colegrove, 2011). ) - Amazon
    • Experimentation: An Introduction to Measurement Theory and Experiment Design, 3rd ed. (DC Baird, 1994) - Amazon
    • Guidelines for evaluating and expressing the uncertainty of NIST measurement results (NIST Technical Note 1927) pdf  - summary
    • Health Research Methodology: A guide for training in research methods, 2nd ed. WHO 2001 - pdf
    • Introduction to Engineering Experimentation, 3rd ed. (AJ Wheeler, AR Ganji, 2009) - Amazon
    • Statistical Experiment Design and Interpretation: An Introduction with Agricultural Examples (CA Collins, FM Seeney, 1999) - Amazon
  • course materials
    • Biology 7610 Experimental Design (CR Chandler) - bibliography
    • Getting Started in Family Medicine Research (S Weaver, Society of Teachers of Family Medicine)
    •  LA Trepanier, U Wisc - 2013 AAVC Residents' Professional Development and Leadership Conference - presentations:
      • Turning a Clinical Question into a Testable Hypothesis - pdf  - video
    • TNM 800: Applied Research Methods
    • Experimental Design Basics (Floyd Bullard, Duke) - pdf
    • Measurement uncertainty instructional resources (D Deardoff, UNC)
      • Definitions of measurement uncertainty terms
      • Introduction to measurements and error analysis - pdf  html
    • Module 1: Experimental design (B Jorgensen) - html  pdf
    • RDF - Researcher Development Program (Australia)
      • PHCRED resources
      • AFP
        • Changing GPs' attitudes to research - Do N of 1 trials hold the key? (D Askew et al. Aust Family Physician 37(7):578-582, 2008) pdf
        • Combining vocational and research training (T olde Hartman, PJ Poels, E Licht-Strunk,. Aust Family Physician 37(6):486-488, 2008) pdf
        • Enabling research in general practice – increasing functionality of electronic medical records (J Young et al. Aust Family Physician 39(7):506-509, 2010) pdf
        • The researcher development program: how to extend the involvement of Australian general practitioners in research? (HH Birden, Rural and Remote Health 7 (online), 2007: 776). html
        • Grassroots research: How to have a stab at your first project and succeed. (E Albert, E Hansen, C Cook, Aust Family Physician 32(7):564-567, 2003) pdf
        • How to undertake research in general practice (N Hiramanek, C Bridges-Webb, Aust Family Physician 33(9):766-768, 2004) pdf
        • Practice based research: Lessons from the field (CF Heal, C Veitch, R Preston, Aust Family Physician 37(5):381-384, 2008)  pdf
    • Research Design (& Methods) Lessons - Karl Wuensch,
    • Research Methodology, EPHTI, 2006, Carter Center - pdf
    • Sweden
      • Research methods courses as a means of developing academic general practice: Fifteen years’ experience from Sweden and Denmark (A Hakansson, Scan J Primary Health Care 23:132-136, 2005) - pdf
      • Research methods courses for GPs: ten years’ experience in southern Sweden (A Hakansson, K Henriksson, A Isacsson, Brit J Gen Pract 50:811-812, 2000) - pdf
    • The Basics of Experimental Design for Multivariate Analysis (SAS paper 284-2009) - pdf
    • UCSF Dept of Epidemiology & Biostatistics (authors of the Clinical Research book)
    • U Ok Residency Research - experimental designs
  • blogs
  • wiki

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Biostatistics Resources - Sample Size:

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Biostatistics Resources - Statistical Analysis

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On-Farm Studies:   Methods for design, execution and analysis

Note: This section focuses on on-farm comparative research resources rather than traditional herd problem and epidemiologic study resources. For the latter, see:

  • papers:
    • Aaron DK, VW Hays (2004). How many pigs? Statistical power considerations in swine nutrition experiments. J Anim Sci 82: E245-E254 html  pdf - WSU access
    • Anon. Some experimental design and statistical criteria for analysis of studies in manuscripts submitted for consideration for publication Animal Feed Sci Techn 129:1-11, 2006 - pdf
    • Bailey JA (1982). Implications of "muddling through" for wildlife management. Wildl Soc Bull 10(4):363-369.  pdf  pdf2
    • Baum DH et al. (2005). Statistical process control methods used to evaluate the serologic responses of pigs infected with three Salmonella serovars. J Swine Health Production 13(6):304–313 - html  pdf
    • Berndtson WE (1991). A simple, rapid and reliable method for selecting or assessing the number of replicates for animal experiments. J Anim Sci 69:67-76 - pdf - WSU access
    • Coe R (2007). Analyzing data from participatory on-farm trials. African Statistics J 4:89-121 - pdf
    • Cripps PJ (2008). Statistical and epidemiological methodology for sheep research: The needs, the problems, the solutions. Small Ruminant Res 76(1-2):26-30 - html
    • DiCostanzo A (2010). Population data analyses to evaluate trends in animal production systems. J Anim Sci 88: E1-E2 - html pdf - WSU access   
    • De Vries A, JK Reneau (2010). Application of statistical process control charts to monitor changes in animal production systems.  J Anim Sci 88: E11-E24 - pdf   pdf2 - WSU access   
    • Dorfman JH (1996). Pseudorandom sampling has a real effect on test size. The American Statistician 50(2):151-155 - pdf
    • Eberhardt LI, Thomas JM (1991). Designing environmental field studies. Ecological Monographs 61(1):53-73, 1991 - pdf
    • Engstrom M, W Sanchez, W Stone, NR StPierre (2010). Applications of population data analysis in on-farm dairy trials. J Anim Sci 88: E25-E31 - html  pdf - WSU access 
    • Ferguson JD, Beede DK, Shaver RD, et al. (2000). A method to analyze production responses in dairy herds. J Dairy Sci 83(7):1530-1542 - pdf - WSU access
    • Galligan D (2005). Economics into practice - Using economics on the dairy farm. Cattle Practice 13:211-217
    • Galligan DT, Chalupa W, Ramberg CF (1991). Application of type-I and type-II errors in dairy farm management decision-making. J Dairy Sci 74(3):902-910 - pdf
    • Gill JL (1987). Biased statistical analysis when the animal is not the experimental unit. JAVMA 190:5-6
    • Gill JL (1989). Statistical aspects of design and analysis of experiments with animals in pens. J Anim Breed Genet 106:321-334
    • Gould WR, RL Steiner (2002). Viewpoint: Improving range science through the appropriate use of statistics. J Range Manage 55(6):526-529. pdf  pdf2
    • Heaton K, DR Zobell, D Cornforth (2006). A successful collaborative research project: Determining the effects of delayed castration on beef cattle production and carcass traits and consumer acceptability.  J Extension 44(2): - html
    • Hurlbert SH (1984). Pseudoreplication and the design of ecological field experiments. Ecol Monogr 54:198–211. pdf  pdf2
    • Jones R, M Langemeir (2010). A review of population data utilization in beef cattle research. J Anim Sci 88: E32-E37 -  html  pdf - WSU access
    • Johnston LJ, Renteria A, Hannon MR (2003). Improving validity of on-farm research. J Swine Health Prod11(5):240-246  html  pdf 
    • Koenig, RJ, M Winger, B Kitchen (2000). Simple, low cost data collection methods for agricultural field studies.  J Extension 38(2): - html
    • Lawrence D, N Christodoulou, J Whish (2007). Designing better on-farm research in Australia using a participatory workshop process. Field Crops Research 104(1-3):157-164 - pdf - WSU access
    • Leman A (1982). The uses of epidemiology in food animal veterinary medicine. Proc 3rd Intl Symp on Vet Epid Econ pdf
    • Lester S, KE Harr, M Rishniw, P Pion (2013). Current quality assurance concepts and considerations for quality control of in-clinic biochemistry testing. JAVMA 242(2):182-192 - pdf
    • Lightfoot C, R Barke (1988). On-farm trials: A survey of methods. Agricultural Administration and Extension 30(1):15-23
    • Luschei EC et al. (2009). Convenience sample of on-farm research cooperators representative of Wisconsin farmers. Weed Technology 23(2):300-307 - abstract
    • Lukas JM, DM Hawkins, ML Kinsel, JK Reneau (2005). Bulk tank somatic cell counts analyzed by statistical process control tools to identify and monitor subclinical mastitis incidence. J Dairy Sci 88(11):3944–3952 - pdf - WSU access
    • Macnab J (1983). Wildlife management as scientific experimentation. Wildl Soc Bull 11(4):397-401. pdf  pdf2
    • Morton J, B Adolph, S Ashley, D Romney (2002). Conceptual, methodological and institutional issues in participatory livestock production research, 2002. Livestock Research for Rural Development 14(4) - html  pdf
    • Murphy DD, BD Noon (1991). Coping with uncertainty in wildlife biology. J Wildl Manage 55(4):773-782.  pdf  pdf2
    • Norman, D, S Freyenberger, B Schurle (1997). County extension agents and on-farm research work: Results of a Kansas survey. J Extension 35(5): - html
    • Polson DD, WE Marsh, GD Dial (1988). Population-based problem solving in swine herds. J Swine Health Production 6(6):267–272 - pdf
    • Pritchett J, D Thilmany, K Johnson (2005). Animal disease economic impacts: A survey of literature and typology of research approaches. Intl Food Agribusiness Mgmt Rev 8(1):23-45 - pdf
    • Robinson PH, J Wiseman, P Uden, G Mateos (2006). Some experimental design and statistical criteria for analysis of studies in manuscripts submitted for consideration for publication. Animal Feed Science and Technology 129:1-11 -  pdf
    • Rzewnicki, PE, R Thompson, GW Lesoing et al. (1998). On-farm experiment designs and implications for locating research sites. Am J Alternative Agric3(4):168-173
    • Sayre NF (2004). Viewpoint: The need for qualitative research to understand ranch management. (J Range Manage 57(6):668-674) - pdf  pdf2
    • Stein T, Martineau G, Morris R, Charette R (1987). A new approach to managing health in swine operations. Can Vet J 28(6):355-362 - pdf
    • St Pierre NR (2007). Design and analysis of pen studies in the animal sciences. J Dairy Sci 90(suppl 1):E87-E99 - pdf
    • St Pierre, LR Jones (1999). Interpretation and design of nonregulatory on-farm feeding trials. J Dairy Sci 82(Suppl. 2):177–182 - pdf
    • Tempelman RJ (2004). Experimental design and statistical methods for classical and bioequivalence hypothesis testing with an application to dairy nutrition studies. J Anim Sci 82:E162-172 - html  pdf - WSU access 
    • Tempelman RJ (2009). Invited review: Assessing experimental designs for research conducted on commercial dairies. J Dairy Sci 92(1):1-15 - html  pdf - WSU access 
    • Thacker BJ (2005). Understanding process capability in statistical process control. J Swine Health Prod 13(1):53-55. html 
    • Tylutki TP, Fox DG (2002). Mooooving toward six sigma. Quality Progress 35(2):34-41.
    • Tylutki TP, Fox DG, McMahon M (2005). Implementation of nutrient management planning on a dairy farm. Prof Anim Sci 20:58-65. - pdf
    • Wester, DV (1992). Viewpoint: Replication, randomization, and statistics in range research, J Range Manage 45(3):285-290. - pdf  pdf2
  • collections:
    • U Reading Statistical Services Center - publications
      • course notes
      • Guidelines to good statistical practice - zipped - pdf site
        • Concepts Underlying the Design of Experiments - pdf
        • On-Farm Trials - Some Biometric Guidelines - pdf
        • Some Basic Ideas of Sampling - pdf
        • One Animal Per Farm? - pdf
        • Statistical Guidelines for Natural Resource Projects - pdf
    • Ruegg PL, ed. (2006). Barnyard Epidemiology and Performance Assessment. Vet Clinics NA Food Anim Pract 22(1) - WSU access
      • Ruegg PL (2006). Basic Epidemiologic Concepts Related to Assessment of Animal Health and Performance. Vet Clin NA- Food Anim Pract 22(1):1-19
      • Kelton DF (2006). Basic Epidemiologic Concepts Related to Assessment of Animal Health and Performance. Vet Clin NA- Food Anim Pract 22(1):21-33 
      • Corbin MJ, D Griffin (2006). Assessing Performance of Feedlot Operations Using Epidemiology. Vet Clin NA- Food Anim Pract 22(1):35-51
      • Rae DO (2006). Assessing Performance of Cow-Calf Operations Using Epidemiology.  Vet Clin NA- Food Anim Pract 22(1):53-74
      • Sanderson MW (2006). Designing and running clinical trials on farms. Vet Clin NA- Food Anim Pract 22(1):103-123
      • Slenning BD (2006). Hood of the truck statistics for food animal practitioners. Vet Clin NA- Food Anim Pract 22(1):149-170
      • Reneau JK, J Lukas (2006). Using statistical process control methods to improve herd performance. Vet Clin NA- Food Anim Pract 22(1):171-193  
      • Galligan D (2006). Economic assessment of animal health performance. Vet Clin NA- Food Anim Pract 22(1):207-227
  • on-line materials:
  • courses and study guides:

other ag-related resources of mine:

wiki:

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Literature Searching & Library Resources:

Duke University Medical Center Library Sites (Connie Schardt per Vicki Croft):

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Reference Management:


Science, Causation, and the Scientific Method:

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Scientific Presentations:

people:

wiki:

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Scientific Writing:

papers:

people:

books:

  • Christopher M, K Young (2012). Writing for Publication in Veterinary Medicine: A practical guide for researchers and clinicians, Wiley-Blackwell on-line
  • Cook, CK (1985). Line by Line: How to improve your own writing (Amazon)
  • Council of Science Editors (2006). The CSE Manual for Authors, Editors, and Publishers, 7th ed. (Amazon)
  • Day RA & B Gastel (2006). How to Write and Publish a Scientific Paper, 6th ed. (Amazon)
    • Eugene Garfield's review of first edition (pdf)
  • Guberman R (2011). Point Made: How to write like the nation's top advocates (Amazon) - website
  • Fine HE & JP Josephson (2001). More Nitty-Gritty Grammar: Not so serious guide to clear communication - (Amazon)
  • Matthews JR and RW (2008). Successful Scientific Writing: A step-by-step guide for the biological and medical sciences, 3rd ed. (Amazon)
  • Silvia PJ (2007). How to Write a Lot: A Practical Guide to Productive Academic Writing (Amazon)
  • Strunk W & EB White (). Elements of Style, (Amazon, Wikipedia Bartleby)

course materials:

  • How to write (and publish) a scientific paper in hydrology (G Bloschl EGU 2011) - pdf

software/websites:

wiki:

blogs:

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Grantsmanship:

university websites:

papers:

  • Inouye, SK, and Fiellin, DA (2005). An evidence-based guide to writing grant proposals for clinical research. Ann Intern Med 142: 274.

texts:

  • PLOS
    • Ten Simple Rules for Getting Grants PLoS Comput Biol 2(2)
  • The Art of Grantsmanship (Jacob Kraicer, University of Toronto)
  • The Scientist
    • How to Wow a Study Section: A Grantsmanship Lession (off site html)
    • Ten Ways to Write a Better Grant (21(1):71)
    • A Winning Strategy for Grant Applications: Focus on Impact 11(9):13 (off site pdf)

    Heilmeier Catechism - wiki

    1. What are you trying to do? What is the problem and why is it hard?
    2. How is it done now, and what are the limitations of the current practice?
    3. What's new in your approach, and why do you think it will be successful?
    4. If you're successful, what difference will it make?
    5. How do our customers get paid?
    6. What are the risks?
    7. How much will it cost?
    8. How long will it take?
    9. What are the mid-term (intermediate results) and final exams? How will you measure progress?

blogs:

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Evidence-based Medicine and Literature:

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Advice:

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Other Information: