Multidrug Sensitivity in Dogs
Some dog breeds are more sensitive to certain drugs than other breeds. Collies
and related breeds, for instance, can have adverse reactions to drugs such as
ivermectin and loperamide (Imodium). At Washington State University's College of
Veterinary Medicine you can get your dog tested for drug sensitivity and keep up
with the latest research.
Drug sensitivities result from a mutation in the multi-drug resistance
gene (MDR1). This gene encodes a protein, P-glycoprotein that is responsible for
pumping many drugs and other toxins out of the brain. Dogs with the mutant gene
cannot pump some drugs out of the brain as a normal dog would, which may result
in abnormal neurologic signs. The result may be an illness requiring an extended
hospital stay - or even death.
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Test Your Dog
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IMPORTANT NOTICE
The discovery of the mutation of the multi-drug resistant gene (mdr1),
establishment of testing procedures, and development of all reagents was
made by Washington State University. It is also a patent protected
diagnostic test offered exclusively by Washington state university that
has not been licensed to any other entity in the united states. It is
licensed in Australia and Europe. Any unlicensed use or marketing of the
patented test is a violation of federal statute under 35 u.s.c. 271.
Unless testing is conducted by Washington State University's veterinary
clinical pharmacology laboratory, Washington state university cannot
control quality and accuracy and consumers may risk receiving inaccurate
results.
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Most Commonly Affected Breeds
Australian Shepherd
Australian Shepherd (Mini)
Collie
Long-haired Whippet
McNab
Silken Windhound
Click here for a complete list
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