College of Veterinary Medicine

Equine Infectious Diseases Research Program

Wendy Brown

Wendy BrownRegents professor in the Department of Veterinary Microbiology and Pathology, Dr. Brown is recognized nationally and internationally for her research on T lymphocyte responses to tick-borne pathogens of cattle and for the use of T lymphocytes to identify promising vaccine antigens. T lymphocytes give animals and humans immunological memory, enabling them to thwart infectious agents that they have previously encountered. They are critically important in neutralizing pathogens, killing microbes, and for directly killing pathogen-infected cells.

Dr. Brown received the Distinguished International Veterinary Immunologist Award in 2004 from the International Union of Immunological Societies. Granted every three years, the award recognizes the best veterinary immunologist in the world during that period. "Dr. Brown’s acquisition of a major grant from NIH in today’s funding climate documents the international regard for her world-class leadership in animal infectious disease research,” said David Prieur, professor and chair of the WSU Department of Veterinary Microbiology and Pathology, in which Dr. Brown is a professor.

The two tick-transmitted pathogens Dr. Brown studies most closely are Babesia bovis, a parasite, and Anaplasma marginale, a bacterium. Both organisms cause anemia and persistent infection in cattle. The antigens that Dr. Brown has identified for cattle pathogens may be useful for developing vaccines against human pathogens as well.

Dr. Brown recently developed a method for rapidly screening pathogen proteins for their ability to prompt an immune response in a host. The method can help researchers working on any infectious disease quickly identify proteins that are good candidates for a vaccine against the disease.

Dr. Brown is now putting her extensive expertise to work to help the EQUID research team identify protective immune responses against important infectious diseases of horses, and to develop effective vaccines against those diseases.

Dr. Brown's Web site
Last Edited: Nov 28, 2011 9:39 AM   

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