Canine Cardiac Genetics
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Subaortic Stenosis in Golden Retrievers Study
We are currently studying the genetics of familial subaortic stenosis
(SAS) in the Golden Retriever Dog. This study aims to identify a possible
genetic defect responsible for this devastating cause of heart disease in
Goldens.
We are currently seeking normal Golden Retrievers and Golden Retrievers
diagnosed with Subaortic Stenosis (SAS) by a veterinary cardiologist.
Participation is easy and involves completion of the form below and
submission of a small amount of blood. This blood sample can be obtained by
your family veterinarian and shipped directly to our lab.
There is no fee for submitting a sample to this study and participation is
completely confidential.
This study has been endorsed by the Golden Retriever Club of America and we
are working with local breed organizations to promote study participation.
If you have any questions about this study - please contact Dr. Joshua Stern
at jstern@vetmed.wsu.edu .
More information on enrolling your Golden
Retriever in our genetic study of SAS and instructions for sample
submission.
**Upcoming cardiology clinic for easy study participation: Evergreen Golden
Retriever Club Specialty Show 9/5/2009 in Auburn Washington. Dr. Stern and
Dr. Meurs will be available at the show to perform screening evaluations,
take blood samples and help get your Golden enrolled in our SAS study.
Aortic Stenosis in the Rottweiler
Subvalvular aortic stenosis is a birth defect of the heart that is known
to be inherited in some breeds of dogs. Dogs that have a mild form of the
disease may live a normal life span, but dogs that are moderately or severly
affected are at a great risk of sudden death and have been shown to have an
average life span of 19 months in one study.
The Rottweiler is a breed that is known to have an inherited form of this
birth defect and we would like to be able to help them with our genetic
studies. We have been collecting DNA samples from affected and unaffected
Rottweilers for some time, but can still use a few more. We hope to start
our molecular studies this fall!
Details
to submit a sample
Boxer Cardiomyopathy
Test for Boxer Arrhythmogenic Right
Ventricular Cardiomyopathy Mutation
The Veterinary Cardiac Genetics Laboratory has a Boxer study currently in
progress but we are not accepting new dogs for this study. However, we
operate a canine Holter service. To learn more about this service, please
visit our
Holter monitoring web pages.
Doberman Pinscher Dilated Cardiomyopathy Study
We are currently looking for DNA samples from adult Doberman pinschers
without dilated cardiomyopathy to serve as controls (the unaffected group)
to advance our study to identify a gene for Doberman pinscher dilated
cardiomyopathy.
Details
