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Fred R. Rurangirwa, BVSc,
Ms, PhD
Associate Professor
My research interest is in vector-infectious agent interaction
especially rickettsial/ehrlichial pathogens. My focus is on the
mechanisms used by these obligate intracellular bacteria, which
alternate between arthropods and vertebrates, to survive and thrive in
the diverse niches. The long term goal is to block transmission of
the pathogens from the vector to the host. I am using the
interaction between Anaplasma marginale, an intraerythrocytic
ehrlichial pathogen of cattle, and Dermacentor andersoni, a
natural vector of A. marginale as a model.
Selected Publications:
- Rurangirwa, F.R., Stiller, D.S.
and Palmer, G.H. Strain diversity in MSP2 expression during tick
transmission of Anaplasma marginale. Infection and Immunity,
68:3023-3027, 2000.
- Palmer, G.H.,
Brown, W.C., and Rurangirwa, F.R. Antigenic variation in the persistence
and transmission of the ehrlichia Anaplasma marginale.
Microbes and Infection, 2:1-10, 2000.
- Palmer, G.H.,
Rurangirwa, F.R., Kocan, K.M., and Brown, W.C. Molecular basis for
vaccine development against the ehrlichial pathogen Anaplasma
marginale. Parasitology Today, 15:281-286, 1999.
- Rurangirwa, F.R., Stiller, D., French, D.M. and Palmer, G.H.
Restriction of major surface protein 2 (MSP2) variants during tick
transmission of the ehrlichia Anaplasma marginale. Proceedings of
the National Academy of Science, USA 96:3171-3176, 1999.
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