Fred R. Rurangirwa
Fred R. Rurangirwa, BVSc, Ms, PhD
Associate Professor
My research interest is in vector-infectious agent interaction
especially rickettsial/ehrlichial
pathogens. My focus is on the
mechanisms used by these obligate
intracellular bacteria, which
alternate between arthropods and
vertebrates, to survive and thrive in
the diverse niches. The long term
goal is to block transmission of
the pathogens from the vector to the
host. I am using the
interaction between
Anaplasma
marginale, an intraerythrocytic
ehrlichial pathogen of cattle, and
Dermacentor andersoni, a
natural vector of
A. marginale
as a model.
Selected Publications:
- Rurangirwa, F.R., Stiller, D.S.
and Palmer, G.H. Strain diversity in
MSP2 expression during tick
transmission of Anaplasma
marginale. Infection and Immunity,
68:3023-3027, 2000.
- Palmer, G.H.,
Brown, W.C., and Rurangirwa, F.R.
Antigenic variation in the persistence
and transmission of the ehrlichia
Anaplasma marginale.
Microbes and Infection, 2:1-10, 2000.
- Palmer, G.H.,
Rurangirwa, F.R., Kocan, K.M., and
Brown, W.C. Molecular basis for
vaccine development against the
ehrlichial pathogen Anaplasma
marginale. Parasitology Today,
15:281-286, 1999.
- Rurangirwa, F.R., Stiller, D., French, D.M. and Palmer, G.H.
Restriction of major surface protein
2 (MSP2) variants during tick
transmission of the ehrlichia
Anaplasma marginale. Proceedings of
the National Academy of Science, USA
96:3171-3176, 1999.
