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Defined the natural occurrence and shedding patterns of
E. coli O157:H7 in cattle herds and in local and regional farm environments
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First recognized
Salmonella Typhimurium DT 104 as an emerging and
zoonotic pathogen in the USA
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Demonstrated contamination of feedstuffs and water sources as
important factors in dissemination of zoonotic pathogens and normal
flora with antimicrobial resistance
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Selected as a Zoonosis Research Unit within the NIH Food and
Waterborne Disease Integrated Research Network
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Built solid collaborations among WSU research faculty, the Washington
Animal Disease Diagnostic Laboratory, and the Washington Department of
Health to promote animal and public health
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Funding Agency Support
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USDA Fund for Rural America
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International Life Sciences Institute
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USDA NRICGP Epidemiologic Approaches to Food Safety
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Food and Drug Administration
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USDA ARS National Alliance for Food safety
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FDIU program. Agricultural Research Center
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National Institutes of Health
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Selected References
2003 Davis MA, Hancock DD, Besser, TE, Rice DH, Hovde CJ, Digiacomo R,
Samadpour M, Call DR. Correlation between geographic distance and
genetic similarity in an international collection of bovine faecal
Escherichia coli O157:H7 isolates. Epidemiol. Infect. 131:923–930
2003 LeJeune JT, Besser TE, Rice DH, Berg J, Stilborn R, Hancock DD, 2003.
Longitudinal study of fecal shedding of Escherichia coli O157:H7 in
feedlot cattle: Predominance and persistence of specific clonal types
despite massive cattle population turnover. Appl. Environ. Microbiol
70:377-84
2003 Khachatryan A, Hancock DD, Besser TE, Call DR. 2003. The role of
calf-adapted Escherichia coli in maintenance of antimicrobial
resistance in dairy calves. Appl Environ Microbiol, Appl Environ
Microbiol. 2004 Feb;70(2):752-7.
2003 Davis MA, Hancock DD, Besser TE, Call DR. 2003 Evaluation of
pulsed-field gel electrophoresis as a tool for determining the degree
of genetic relatedness between strains of Escherichia coli O157:H7. J Clin Microbiol. 41:1843-9
2003 Call DR, Borucki MK, Besser TE. 2003. Mixed-genome
microarrays reveal multiple serotype and lineage-specific differences
among strains of Listeria monocytogenes. J Clin Microbiol. 41:632-9.
2001 LeJeune JT, Hancock DD, Besser TE. Cattle water troughs as
reservoirs of Escherichia coli O157. Applied Environ Microbiol,
67:3053-60
2001 Besser TE, Richards BL, Rice DH, Hancock DD.
Escherichia coli
O157:H7 infection of calves: Infectious dose and direct contact
transmission. Epidemiol Infect, 127:555-60
2000 Sanderson MW, JM Gay, TV Baszler.
Neospora caninum seroprevalence
and associated risk factors in beef cattle in the northwestern United
States. Vet Parasitol 90:15-24.
2000 Pritchett LC, ME Konkel, JM Gay, TE Besser. Identification of
DT104 and U302 phage types among Salmonella enterica serotype
Typhimurium by PCR. J Clin Micro. 38:3484-8.
2000
Besser TE, M Goldoft, LC Pritchett, R Khakhria, DD Hancock, DH Rice,
JM Gay, W Johnson, CC Gay. Multiresistant Salmonella Typhimurium DT104
infections of humans and domestic animals in the Pacific Northwest of
the United States. Epidemiol Infect 124:193-200.
1999 Davis MA, DD Hancock, TE Besser, DH Rice, JM Gay, C Gay, L
Gearhart, R DiGiacomo. Changes in antimicrobial resistance among
Salmonella enterica serovar Typhimurium isolates from humans and
cattle in the Northwestern United States, 1982-1997. Emerg Infect Dis
5:802-6.
1999 Sanderson MW, TE Besser, JM Gay, CC Gay CC, DD Hancock. Fecal
Escherichia coli O157:H7 shedding patterns of orally inoculated calves.Vet Microbiol 69:199-205.
1998 Krytenburg DS, DD Hancock, DH Rice, TE Besser, CC Gay, JM Gay.
(1998) A pilot survey of Salmonella enterica contamination of cattle
feeds in the Pacific northwestern USA.. Anim Feed Sci Tech 75:75-79.
*Graduate Students and Post-doctoral trainees in BOLD
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