Melatonin - it's not just a sleep hormone!
" A pilot study: serum melatonin levels in normal dogs and dogs with
Purpose of Study
Epilepsy or recurrent seizures are reported to be the most common
neurologic conditions in dogs, but 20-30% of affected dogs are
considered to be resistant to the commonly used canine anticonvulsant
drugs. Thus, alternative canine epilepsy treatments are needed.
The purpose of this study is to compare melatonin levels in normal dogs
with levels in dogs who experience seizures. Recent studies of lab
animals have shown that the hormone melatonin has anti-seizure
properties. According to several case reports in human medicine,
melatonin may also reduce seizures in people.
This study may lay the groundwork for further studies that examine
the effects of melatonin on seizures, leading to the development of new
seizure treatments utilizing melatonin. Enrolled dogs will receive
a free examination by a board certified veterinary neurologist.
All costs associated with blood draws and analysis will be covered by
Normal dogs: We have completed enrollment for normal dogs at
this time. Thank you for your interest.
Seizure dogs: Dogs enrolled in this study must have a
documented history of seizures. They can be any breed, sex or weight
but must be older than 6 months of age.
Enrolled dogs will spend one day (7:30-4:30) at the WSU-VTH.
Upon arrival, they will receive a thorough physical exam including a
detailed neurologic exam. A neurologist will draw 6.0 ml of blood
(a little over 1 teaspoon) from the dog three times during the day (at 8
am, 12 pm and 4 pm).
Bring your dog to the WSU-VTH for one day (7:30-4:30).
For more information please contact either Valorie Wiss, Clinical
Studies Coordinator (Office: 509-335-0798, Cell: 509-432-5345 or
email@example.com), or Dr.
Stephanie Thomovsky (509-335-0711).