Rebecca Craft, Ph.D.
Phone: (509) 335-5040
Office: Johnson Tower 233D
The primary goal of my laboratory is to determine the neurobiological
mechanisms underlying sex differences in behavioral effects of CNS
Using animal models, we (1) characterize sex differences in the
psychopharmacological effects of CNS drugs; and (2) determine how
gonadal steroid hormones such as testosterone and estradiol modulate
pain, mood, and the therapeutic and side-effects of psychoactive drugs
such as opioids (e.g., morphine) and cannabinoids (e.g, THC). The
clinical applications of this work are (1) the development of
sex-appropriate guidelines for use of psychotherapeutic, analgesic and
anesthetic medications; and (2) improved prevention and treatment of
gonadal steroid hormone-mediated pain and depression.
For more information on my lab go to
Rebecca M. Craft, Associate Professor, completed the B.S. degree in
animal science at the University of Maryland in 1981, the M.S. degree in
zoology (animal behavior) at North Carolina State University in 1984,
and the Ph.D. degree in experimental and biological psychology at the
University of North Carolina in 1991. She was a postdoctoral fellow in
the Department of Pharmacology at the University of Arizona and has been
at Washington State University since 1993.
Modulation of pain by estrogens.
Pain 132: S3-S12, 2007.
Sex differences in analgesic, reinforcing, discriminative and
motoric effects of opioids.
Experimental and Clinical Psychopharmacology 16:376-385, 2008.
Navarre BM, Laggart JD, Craft RM:
Anhedonia in postpartum rats. Physiology and Behavior
Wakley AA, Craft RM:
Antinociceptive and motoric effects of intracerebroventricular delta9
tetrahydrocannabinol in female vs. male rats. Behavioural Brain Research