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My research focuses on the effects of sleep and
sleep deprivation on neurobehavioral functions. I conduct experiments with
human volunteers staying in the laboratory for multiple days (up to 2
weeks). These studies provides insight into the interactions of time awake
versus time asleep (i.e., sleep homeostasis), circadian rhythms, and other
regulatory mechanisms affecting waking neurobehavioral performance. I am
particularly interested in inter-individual differences in sleep
architecture and in the cognitive responses to sleep loss, having
demonstrated that these inter-individual differences constitute
neurobiological traits. In addition, I am engaged in mathematical and
statistical modeling of the temporal changes in performance across extended
periods of wakefulness. Many students are actively involved in conducting
the experiments and analyzing the data underlying this research.
WSU Sleep and Performance Research Center. Pictured (l-r) are
Drs. David
Rector, Hans Van Dongen, Gregory Belenky, and
(sitting) James Krueger.
Biographical Information
Associate Research
Professor, Sleep and Performance Research Center, Washington State
University Spokane, October 2005-present.
Research Associate Professor of Sleep and Chronobiology, Department of
Psychiatry, University of Pennsylvania, July 2004-September 2005.
Research Assistant Professor of Sleep and Chronobiology, Department of
Psychiatry, University of Pennsylvania, July 1999-June 2004.
Postdoctoral Researcher, Department of Psychiatry, University of
Pennsylvania, June 1998-June 1999.
Ph.D. degree in Chronobiology and Sleep, 1998, Leiden University, The
Netherlands.
M.S. degree in Astrophysics, 1993, Leiden University, The Netherlands
Selected Recent Publications
Van Dongen HPA, Caldwell Jr JA, Caldwell JL.
Investigating systematic individual differences in sleep-deprived
performance on a high-fidelity flight simulator. Behavior Research
Methods 2006; 38(2): 333-343.
Van Dongen HPA. Shift work and inter-individual differences in sleep and
sleepiness. Chronobiology International 2006; 23(6): 1139-1147.
Van Dongen HPA, Vitellaro KM, Dinges DF. Individual differences in adult
human sleep and wakefulness: Leitmotif for a research agenda. Sleep
2005; 28(4): 479-496.
Van Dongen HPA, Olofsen E, Dinges DF, Maislin G. Mixed-model regression
analysis and dealing with interindividual differences. Methods in
Enzymology 2004; 384: 139-171.
Van Dongen HPA, Baynard MD, Maislin G, Dinges DF. Systematic interindividual
differences in neurobehavioral impairment from sleep loss: Evidence of
trait-like differential vulnerability. Sleep 2004; 27(3): 423-433.
Van Dongen HPA. Comparison of mathematical model predictions to experimental
data of fatigue and performance. Aviation, Space, and Environmental
Medicine 2004; 75(3): A15-A36.
Van Dongen HPA, Rogers NL, Dinges DF. Sleep debt: Theoretical and empirical
issues. Sleep and Biological Rhythm 2003; 1: 5-13.
Van Dongen HPA, Maislin G, Mullington JM, Dinges DF. The cumulative cost of
additional wakefulness: Dose-response effects on neurobehavioral functions
and sleep physiology from chronic sleep restriction and total sleep
deprivation. Sleep 2003; 26(2): 117-126.
Van Dongen HPA, Dinges DF. Investigating the interaction between the
homeostatic and circadian processes of sleep-wake regulation for the
prediction of waking neurobehavioural performance. Journal of Sleep
Research 2003; 12(3): 181-187.
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