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An Alphabetized List of PAgesAn Alphabetized List of PAges
  James M. Krueger, Ph.D.    
 


Additional Publications

Krueger, J.M. Ph.D. Dissertation: 1974. Binding of L-alanine to a preparation from taste epithelium of the catfish Ictalurus punctatus.

Pappenheimer, J.R., G. Koski, V. Fencl, M.L. Karnovsky, and J.M. Krueger. 1975. Extraction of sleep-promoting Factor S from cerebrospinal fluid and from brains of sleep-deprived animals. J. Neurophysiol. 38: 1299-1311.

Krueger, J.M., and R.H. Cagan. 1976. Biochemical studies of taste sensation: binding of L-3(H)-alanine to a sedimentable fraction from catfish barbel epithelium. J. Biol. Chem. 251: 88-97.

Krueger, J.M., N. Sokoloff, and S.Y. Botelho. 1976. Sialic acid in rabbit lacrimal gland fluid. Invest. Ophthalmol. 15: 479-481.

Krueger, J.M., J.R. Pappenheimer, and M.L. Karnovsky. 1978. Sleep-promoting Factor S: purification and properties. Proc. Natl. Acad. Sci. USA 75: 5235-5238.

Krueger, J.M., J. Bacsik, and J. García-Arrarás. 1980. Sleep-promoting material from human urine and its relation to Factor S from brain. Am. J. Physiol. 238: E116-E123.

Pappenheimer, J.R., J.M. Krueger, and J. Garcia-Arraras. 1981. Properties of sleep-promoting Factor S derived from human urine. In: Advanced Physiology Science. Vol. 18: "Environmental Physiology." F. Obál and G. Benedec (eds.).

Krueger, J.M., J.R. Pappenheimer, and M.L. Karnovsky. 1982. The composition of sleep-promoting factor isolated from human urine. J. Biol. Chem. 257: 1664-1669.

Krueger, J.M. Sleep-promoting Factor S: characterization and analogs. 1983. In: Sleep 1982. W.P. Koella (ed.). Karger; pp. 107-109.

Krueger, J.M., J.R. Pappenheimer, and M.L. Karnovsky. 1982. Sleep-promoting effects of muramyl peptides. Proc. Natl. Acad. Sci. (USA) 79: 6102-6106.

Krueger, J.M., J. Walter, M. Karnovsky, L. Chedid, J.P. Choay, P. Lefrancier, and E. Lederer. 1984. Muramyl peptides: variation of somnogenic activity with structure. J. Exp. Med. 159: 68-76.

Krueger, J.M., J. Walter, C.A. Dinarello, S.M. Wolff, and L. Chedid. 1984. Sleep-promoting effects of endogenous pyrogen (interleukin-1). Am. J. Physiol. 246: R994-R999.

Chedid, L., G.M. Bahr, G. Riveau, and J.M. Krueger. 1984. Specific absorption with monoclonal antibodies to muramyl dipeptide of the pyrogenic and somnogenic activities of rabbit monokine. Proc. Natl. Acad. Sci. (USA) 81: 5888-5891.

Martin, S.A., M.L. Karnovsky, J.M. Krueger, J.R. Pappenheimer, and K. Biemann. 1984. Peptidoglycans as promoters of slow-wave sleep. I. Structure of sleep-promoting factor isolated from human urine. J. Biol. Chem. 259: 12652-12658.

Krueger, J.M., M.L. Karnovsky, S.A. Martin, J.R. Pappenheimer, J. Walter, and K. Biemann. 1984. Peptidoglycans as promoters of slow-wave sleep. II. Somnogenic and pyrogenic activities of some naturally occurring muramyl peptides; correlations with mass spectrometric structure determination. J. Biol. Chem. 259: 12659-12662.

Krueger, J.M. 1985. Somnogenic activity of muramyl peptides. Trends Pharmachol.. Sci. 6: 218-221.

Krueger, J.M., J. Walter, and C. Levin. 1985. Factor S and related somnogens: an immune theory for slow-wave sleep. In: Brain Mechanisms of Sleep. D. McGinty, et al. (eds.). Raven Press; pp. 253-276.

Krueger, J.M. 1985. Endogenous sleep factors. In: Sleep: Neurotransmitters and Neuromodulators. A. Wauquier (ed.). Raven Press; pp. 319-331.

Krueger, J.M. 1985. Muramyl peptides and interleukin-1 as promoters of slow wave sleep. In: Endogenous Sleep Substances and Sleep Regulation. S. Inoué and A.A. Borbély (eds.). Japan Scientific Societies Press: Tokyo, JAPAN; pp. 181-192.

Krueger, J.M., J. Walter, C.A. Dinarello, and L. Chedid. 1985. Induction of slow-wave sleep by interleukin-1. Progr. Leukocyte Biol. 2: 161-170.

Moldofsky, H., J.M. Krueger, J. Walter, C.A. Dinarello, F.A. Lue, G. Quance, and D.G. Oreopoulos. 1985. Sleep-promoting material extracted from peritoneal dialysate of patients with end-stage renal disease and insomnia. Peritoneal Dialysis Bull. 5: 189-193.

Krueger, J.M. 1985. Interleukin-1: a promoter of slow-wave sleep. In: Neuroimmuno-modulation. N.H. Spector (Editor-in-Chief). IWGN: Bethesda, MD; pp. 99-102.

Krueger, J.M. 1986. Muramyl peptide enhancement of slow-wave sleep. Meth. Findings Exp. Clin. Pharmacol. 8: 105-110.

Krueger, J.M. 1986. Somnogenic muramyl peptides. In: Biological Properties of Peptidoglycan. H.P. Seidl and K.H. Schleifer (eds.). Walter Degruyter & Co.: Berlin, GEMANY; pp. 329-334.

Krueger, J.M., and S. Shoham. 1986. Homologies between sleep factors and hibernation triggers. In: Living in the Cold. H.C. Heller (ed.). Elsevier Scientific Publishing Co.: New York, NY; pp. 235-244.

Krueger, J.M., S. Shoham, and D. Davenne. 1986. Immune modulators as promoters of slow wave sleep. Clin. Neuropharmacol. 9: 462-464.

Walter, J., D. Davenne, S. Shoham, C.A. Dinarello, and J.M. Krueger. 1986. Brain temperature changes coupled to sleep states persist during interleukin 1-enhanced sleep. Am. J. Physiol. 250: R96-R103.

Silverman, D.H.S., J.M. Krueger, and M.L. Karnovsky. 1986. Specific binding sites for muramyl peptides on murine macrophages. J. Immunol. 136: 2195-2201.

Dinarello, C.A., and J.M. Krueger. 1986. Induction of interleukin-1 by synthetic and naturally occurring muramyl peptides. Fed. Proc. 45: 2545-2548.

Krueger, J.M., J.W. Karaszewski, D. Davenne, and S. Shoham. 1986. Somnogenic muramyl peptides. Fed. Proc. 45: 2552-2555.

Krueger, J.M., S. Kubillus, S. Shoham, and D. Davenne. 1986. Enhancement of slow-wave sleep by endotoxin and lipid A. Am. J. Physiol. 251: R591-R597.

Krueger, J.M., and M.L. Karnovsky. 1987. Sleep and the immune response. Ann. N.Y. Acad. Sci. 496: 510-516.

Rosenthal, R.S., and J.M. Krueger. 1988. Promotion of sleep by gonococcal peptidoglycan fragments: structural requirements for somnogenic activity. In: Gonococci and Meningococci. J.T. Poolman, H.C. Zonen, and E.C. Beuvery (eds.). Kluwer Academic Publishers: Dordrecht; pp. 581-590. 1987. Antonie Van Leeuwenhoek 53: 523-32.

Krueger, J.M., R.S. Rosenthal, S.A. Martin, J. Walter, D. Davenne, S. Shoham, S.L. Kubillus, and K. Biemann. 1987. Bacterial peptidoglycans as modulators of sleep: I. Anhydro forms of muramyl peptides enhance somnogenic potency. Brain Res. 403: 249-257.

Krueger, J.M., D. Davenne, J. Walter, S. Shoham, S.L. Kubillus, R.S. Rosenthal, S.A. Martin, and K. Biemann. 1987. Bacterial peptidoglycans as modulators of sleep: II. Effects of muramyl peptides on the structure of rabbit sleep. Brain Res. 403: 258-266.

Krueger, J.M., C.A. Dinarello, S. Shoham, D. Davenne, J. Walter, and S. Kubillus. 1987. Interferon alpha-2 enhances slow-wave sleep in rabbits. Int. J. Immunopharmacol. 9: 23-30.

Shoham, S., R.A. Ahokas, C.M. Blatteis, and J.M. Krueger. 1987. Effects of muramyl dipeptide on sleep, body temperature and plasma copper after intracerebral ventricular administration. Brain Res. 419: 223-228.

Shoham, S., D. Davenne, A.B. Cady, C.A. Dinarello, and J.M. Krueger. 1987. Recombinant tumor necrosis factor and interleukin 1 enhance slow-wave sleep. Am. J. Physiol. 253: R142-R149.

Davenne, D., and J.M. Krueger. 1987. Enhancement of quiet sleep in rabbit neonates by muramyl dipeptide. Am. J. Physiol. 253: R646-R654.

Shoham, S., D. Davenne, and J.M. Krueger. 1987. Muramyl dipeptide, amphetamine, and physostigmine: Effects on sleep of rabbits. Physiol. Behav. 41: 179-185.

Davenne, D., and J.M. Krueger. 1988. Quiet sleep in neonates is enhanced by muramyl dipeptide. In: Sleep 1986. W.P. Koella, F. Obál, H. Schulz and P. Visser (eds.). Gustav Fisher Verlag: New York, NY; pp. 178-179.

Krueger, J.M., L.A. Toth, A.B. Cady, L. Johannsen, and F. Obál, Jr. 1988. Immunomodulation and sleep. In: Sleep Peptides: Basic and Clinical Approaches. S. Inoué and D. Schneider-Helmert (eds.). Japan Scientific Society Press: Tokyo/Berlin; Springer-Verlag; pp. 95-129.

Johannsen, L., and J.M. Krueger. 1988. Quantitation of diaminopimelic acid in human urine. Adv. Biosci. 68: 445-449.

Shoham, S., and J.M. Krueger. 1988. Muramyl dipeptide-induced sleep and fever: Effects of ambient temperature and time of injections. Am. J. Physiol. 255: R157-R165.

Obál, Jr., F., P. Alföldi, A.B. Cady, L. Johannsen, G. Sáry, and J.M. Krueger. 1988. Growth hormone-releasing factor enhances sleep in rats and rabbits. Am. J. Physiol. 255: R310-R316.

Toth, L.A., and J.M. Krueger. 1988. Alteration of sleep in rabbits by Staphylococcus aureus infection. Infect. Immun. 56: 1785-1791.

Krueger, J.M., J.A. Majde, C.M. Blatteis, J. Endsley, R.A. Ahokas, and A.B. Cady. 1988. Polyriboinosinic:polyribocytidylic acid (Poly I:C) enhances rabbit slow-wave sleep. Am. J. Physiol. 255: R748-R755.

Opp, M.R., F. Obál, Jr., and J.M. Krueger. 1988. Effects of a -MSH on sleep, behavior, and brain temperature: interactions with IL1. Am. J. Physiol. 255: R914-R922.

Krueger, J.M., L.A. Toth, L. Johannsen, F. Obál, Jr., M. Opp, and A.B. Cady. 1988. Enhancement of mammalian sleep by immune modulators. In: Advances in Immunopharmacology 4. Hadden, et al. (eds.). Pergamon Press: New York, NY; pp. 55-63.

Krueger, J.M., and L. Johannsen. 1988. Bacterial products, cytokines and sleep. In: Molecular Mimicry in Health and Disease. A. Lernmark, T. Dyrberg, L. Terenius, and B. Hökfelt (eds.). Elsevier: Amsterdam, NETHERLANDS; pp. 35-46.

Walter, J.S., P. Meyers, and J.M. Krueger. 1989. Microinjection of interleukin-1 into brain: Separation of sleep and fever responses. Physiol. Behav. 45: 169-176.

Obál, Jr., F., M. Opp, A. Cady, L. Johannsen, P. Alföldi, and J.M. Krueger. 1989. Links between neuroendocrine processes and sleep regulation. In: Sleep '88. W.P. Koella (ed.). Fischer: Stüttgart, GERMANY; pp. 74-76.

Opp, M., F. Obál, Jr., and J.M. Krueger. 1989. Alpha-MSH inhibits normal and IL1-induced excess sleep in rabbits. In: Sleep '88. W.P. Koella (ed.). Fischer: Stüttgart, GERMANY; pp. 145-146.

Shoham, S., C.M. Blatteis, and J.M. Krueger. 1989. Effects of preoptic area lesions on muramyl dipeptide-induced sleep and fever. Brain Res. 476: 396-399.

Cady, A.B., S. Kotani, T. Shiba, S. Kusumoto, and J.M. Krueger. 1989. Somnogenic activities of synthetic lipid A. Infect. Immun. 57: 396-403.

Obál, Jr., F., M. Opp, A.B. Cady, L. Johannsen, and J.M. Krueger. 1989. Prolactin, vasoactive intestinal peptide, and peptide histidine methionine elicit selective increases in REM sleep in rabbits. Brain Res. 490: 292-300.

Toth, L.A., and J.M. Krueger. 1989. Hematologic effects of exposure to three infective agents in rabbits. J. Am. Vet. Med. Assoc. 195: 981-986.

Krueger, J.M., F. Obál, Jr., L. Johannsen, A.B. Cady, and L. Toth. 1989. Endogenous slow wave sleep substances. In: Slow Wave Sleep: Physiological, Pathophysiological and Functional Aspects. A. Wauquier, C. Dugovic, and M. Radulovacki (eds.). Raven Press: New York, NY; pp. 75-90.

Shibata, M., C.M. Blatteis, J.M. Krueger, F. Obál, Jr., and M. Opp. 1989. Pyrogenic, inflammatory, and somnogenic responses to cytokines: differential modes of action. In: Thermoregulation: Research and Clinical Applications. P. Lomax, et al. (eds.). Karger: Basel; pp. 69-73.

Toth, L.A., and J.M. Krueger. 1989. Effects of microbial challenge on sleep in rabbits. FASEB-J. 3: 2062-2066.

Krueger, J.M. 1989. No simple slumber. The Sciences May/June Issue: 36-41.

Opp, M., F. Obál, Jr., A.B. Cady, L. Johannsen, and J.M. Krueger. 1989. Interleukin-6 is pyrogenic but not somnogenic. Physiol. Behav. 45: 1069-1072.

Opp, M., F. Obál, Jr., and J.M. Krueger. 1989. Corticotropin-releasing factor attenuates interleukin 1-induced sleep and fever in rabbits. Am. J. Physiol. 257: R528-R535.

Krueger, J.M., F. Obál, Jr., M. Opp, L. Johannsen, A.B. Cady, and L. Toth. 1989. Immune response modifiers and sleep. In: Interactions Among Central Nervous System, Neuroendocrine and Immune Systems. J.W. Hadden, K. Masek and G. Nistico (eds.). Pythagora Press: Rome, ITALY; pp. 323-350.

Cady, A.B., G. Riveau, L. Chedid, C.A. Dinarello, L. Johannsen, and J.M. Krueger. 1989. Interleukin-1-induced sleep and febrile responses differentially altered by a muramyl dipeptide derivative. Int. J. Immunopharmac. 11: 887-893.

Johannsen, L., R.S. Rosenthal, S.A. Martin, A.B. Cady, F. Obál, Jr., M. Guinand, and J.M. Krueger. 1989. Somnogenic activity of O-acetylated and dimeric muramyl peptides. Infect. Immun. 57: 2726-2732.

Krueger, J.M., and L. Johannsen. 1989. Bacterial products, cytokines and sleep. J. Rheumato. 16: 52-57.

Krueger, J.M., F. Obál, Jr., M. Opp, L. Toth, L. Johannsen, and A.B. Cady. 1990. Somnogenic cytokines and models concerning their effects on sleep. Yale J. Biol. Med. 63: 157-172.

Johannsen, L., L.A. Toth, R.S. Rosenthal, M.R. Opp, F. Obál, Jr., A.B. Cady, and J.M. Krueger. 1990. Somnogenic, pyrogenic, and hematologic effects of bacterial peptidoglycan. Am. J. Physiol. 259: R182-R186.

Toth, L.A., and J.M. Krueger. 1990. Somnogenic, pyrogenic, and hematologic effects of experimental pasteurellosis in rabbits. Am. J. Physiol. 258: R536-R542.

Krueger, J.M. 1990. Somnogenic activity of immune response modifiers. Trends Pharma. Sci. 11: 122-126.

Krueger, J.M., and J.A. Majde. 1990. Sleep as a host defense: its regulation by microbial products and cytokines. Clin. Immunol. Immunopathol. 57: 188-199.

Krueger, J.M., L.A. Toth, L. Johannsen, and M.R. Opp. 1990. Infectious disease and sleep: Involvement of neuroendocrine-neuroimmune mechanisms. Int. J. Neurosci. 51: 359-362.

Krueger, J.M., F. Obál, Jr., M. Opp, A.B. Cady, L. Johannsen, L.A. Toth, and J.A. Majde. 1990. Putative sleep neuromodulators. In: Sleep and Biological Rhythms. J. Montplaisir and R. Godbout (eds.). Oxford Press: New York, NY; pp. 163-185.

Krueger, J.M., F. Obál, Jr., L. Toth, L. Johannsen, A.B. Cady, and M. Opp. 1990. Sleep factors: models concerning their multiple interactions and specificity for sleep. In: Endogenous Sleep Factors. S. Inoué and J.M. Krueger (eds.). SPB Academic Publishing; pp. 19-29.

Obál, Jr., F., M. Opp, G. Sáry, and J.M. Krueger. 1990. Endocrine mechanisms in sleep regulation. In: Endogenous Sleep Factors. S. Inoué and J.M. Krueger (eds.). SPB Academic Publishing; pp. 109-120.

Krueger, J.M., F. Obál, Jr., L. Johannsen, M. Opp, L.A. Toth, and A.B. Cady. 1990. Endogenous sleep factors: relationships to physiological variables. In: Sleep and Respiration. F.G. Issa, P.M. Suratt, and J.E. Remmers (eds.). Wiley Liss: New York, NY; pp. 1-8. 1990; Prog. Clin. Biol. Res. 345: 1-8.

Krueger, J.M., M.R. Opp, L.A. Toth, L. Johannsen, and L. Kapás. 1990. Cytokines and sleep. In: Current Topics in Neuroendocrinology. Vol. 10: "Behavioral Aspects of Neuroendocrinology." D. Ganten and D. Pfaff (eds.). Springer-Verlag: Berlin, GERMANY; pp. 243-261.

Opp, M.R., F. Obál, Jr., L. Payne, and J.M. Krueger. 1990. Responsiveness of rats to interleukin-1: Effects of monosodium glutamate treatment of neonates. Physiol. Behav. 48: 451-457.

Obál, Jr., F., M. Opp, A.B. Cady, L. Johannsen, A.E. Postlethwaite, H.M. Poppleton, J.M. Seyer, and J.M. Krueger. 1990. Interleukin 1a and an interleukin 1b fragment are somnogenic. Am. J. Physiol. 259: R439-R446.

Opp, M.R., and J.M. Krueger. 1990. IL-6: A pyrogenic cytokine that is not somnogenic. In: The Physiological and Pathological Effects of Cytokines. M. Kluger, J.J. Oppenheim, C.A. Dinarello and M. Powanda (eds.). Wiley-Liss, Inc.; pp. 319-324.

Krueger, J.M., M. Opp, L.A. Toth, and L. Kapás. 1990. Immune regulation, hormones, and sleep. In: Sleep '90. J. Horne (ed.). Pontenagel Press: Bochum; pp. 371-374.

Toth, L.A., and J.M. Krueger. 1990. Infectious disease, cytokines and sleep. In: The Diencephalon and Sleep. M. Mancia (ed.). Raven Press: New York, NY; pp. 331-341.

Opp, M.R., F. Obál, Jr., and J.M. Krueger. 1991. Interleukin-1 alters rat sleep: temporal and dose-related effects. Am. J. Physiol. 260: R52-R58.

Johannsen, L., J. Wecke, F. Obál, Jr., and J.M. Krueger. 1991. Macrophages produce somnogenic and pyrogenic muramyl peptides during the digestion of staphylococci. Am. J. Physiol. 260: R126-R133.

Majde, J.A., R.K. Brown, M.W. Jones, C.W. Dieffenbach, N. Maitra, J.M. Krueger, A.B. Cady, C.W. Smitka, and H.F. Maassab. 1991. Detection of toxic viral-associated double-stranded RNA (dsRNA) in influenza-infected lung. Microbial Pathogen. 10: 105-115.

Opp, M.R., and J.M. Krueger. 1991. Interleukin 1 receptor antagonist blocks interleukin 1-induced sleep and fever. Am. J. Physiol. 260: R453-R457.

Kapás, L., L. Payne, F. Obál, Jr., M. Opp, L. Johannsen, and J.M. Krueger. 1991. Sleep in diabetic rats: effects of interleukin 1. Am. J. Physiol. 260: R995-R999.

Kapás, L., F. Obál, Jr., I. Farkas, L.C. Payne, G. Sáry, G. Rubicsek, and J.M. Krueger. 1991. Cholecystokinin promotes sleep and reduces food intake in diabetic rats. Physiol. Behav. 50: 417-420.

Obál, Jr., F., L. Payne, L. Kapás, M. Opp and J.M. Krueger. 1991. Inhibition of growth hormone-releasing hormone suppresses both sleep and growth hormone secretion in the rat. Brain Res. 557: 149-153.

Johannsen, L., H. Labischinski, and J.M. Krueger. 1991. Somnogenic activity of pseudomurein in rabbits. Infection Immunity 59: 2502-2504.

Krueger, J.M., L. Johannsen, L.A. Toth, M. Opp, and L. Kapás. 1991. CNS mechanisms for sleep responses to microbial challenge. In: Peripheral Signaling of the Brain. Neural-immune and Cognitive Function. (Proceedings of the 6th International Symposium on Neuronal Control of Bodily Function: Basic and Clinical Aspects.) R.C.A. Frederickson, J.L. McGaugh and D.L. Felten (eds.). Hogrefe & Huber Publishers: Toronto, Quebec, CANADA; pp. 179-192.

Krueger, J.M., L.A. Toth, F. Obál, Jr., M.R. Opp, M. Kimura-Takeuchi, and L. Kapás. 1991. Infections, cytokines and sleep. In: Sleep Hormones and Immunological System. S. Smirne (ed.). Masson Editor: Milano, ITALY; pp. 59-70.

Hong, L., L. Johannsen, and J.M. Krueger. 1991. Modulation of human leukocyte antigenDR expression in glioblastoma cells by interferon gamma and other cytokines. J. Neuroimmunol. 35: 139-152.

Kapás, L., F. Obál, Jr., M.R. Opp, L. Johannsen, and J.M. Krueger. 1991. Intraperitoneal injection of cholecystokinin elicits sleep in rabbits. Physiol. Behav. 50: 1241-1244.

Obál, Jr., F., L. Payne, M. Opp, L. Kapás, P. Alföldi, and J.M. Krueger. 1991. Hypothalamic Releasing Hormones in Sleep Regulation. In: Sleep Hormones and Immunological System. S. Smirne (ed.). Masson Editor: Milano, ITALY; pp. 91-98.

Krueger, J.M., M.R. Opp, L. Kapás, M. Kimura-Takeuchi, and L. Toth. 1992. Muramyl peptides and interleukin-1 in sleep regulation. In: Endocrine and Nutritional Control of Basic Biological Functions. R. Murison, (ed.). Hogrefe & Huber Publishers: Toronto, Quebec, CANADA; pp. 343-349.

Opp, M.R., and J.M. Krueger. 1992. Interleukin-1 involvement in the regulation of sleep. In: Interleukin-1 in the Brain. N. Rothwell and R. Dantzer, (eds.). Manchester University Press: Manchester; pp. 151-172.

Krueger, J.M., L. Kapás, M.R. Opp, and F. Obál, Jr. 1992. Prostaglandins E2 and D2 have little effect on rabbit sleep. Physiol. Behav. 51: 481-485.

Payne, L., F. Obál, Jr., M.R. Opp, and J.M. Krueger. 1992. Stimulation and inhibition of growth hormone secretion by interleukin-1b : the involvement of growth hormone-releasing hormone. Neuroendocrinology 56: 118-123.

Opp, M.R., A.E. Postlethwaite, J.M. Seyer, and J.M. Krueger. 1992. Interleukin 1 receptor antagonist blocks somnogenic and pyrogenic responses to an interleukin 1 fragment. PNAS. 89: 3726-3730.

Kapás, L., and J.M. Krueger. 1992. Tumor necrosis factor-b induces sleep, fever, and anorexia. Am. J. Physiol. 263: R703-R707.

Kapás, L., L. Hong, A.B. Cady, M.R. Opp, A.E. Postlethwaite, J.M. Seyer, and J.M. Krueger. 1992. Somnogenic, pyrogenic, and anorectic activities of tumor necrosis factor-a and TNF-a fragments. Am. J. Physiol. 263: R708-R715.

Kimura-Takeuchi, M., J.A. Majde, L.A. Toth, and J.M. Krueger. 1992. Influenza virus-induced changes in rabbit sleep and acute phase responses. Am. J. Physiol. 263: R1115-R1121.

Obál, Jr., F., L. Payne, M. Opp, P. Alföldi, L. Kapás, and J.M. Krueger. 1992. Growth hormone-releasing hormone antibodies suppress sleep and prevent enhancement of sleep after sleep deprivation. Am. J. Physiol. 263: R1078-R1085.

Toth, L.A., T.W. Gardiner, and J.M. Krueger. 1992. Modulation of sleep by cortisone in normal and bacterially infected rabbits. Am. J. Physiol. 263: R1339-R1346.

Payne, L.C., and J.M. Krueger. 1992. Interactions of cytokines with the hypothalamic-pituitary axis. J. Immunother. 12: 171-173.

Obál, Jr., F., B. Kacsóh, P. Alföldi, L. Payne, O. Markovic, C. Grosvenor, and J.M. Krueger. 1992. Antiserum to prolactin decreases rapid eye movement sleep (REM Sleep) in the male rat. Physiol. Behav. 52: 1063-1068.

Kimura-Takeuchi, M., J.A. Majde, L.A. Toth, and J.M. Krueger. 1992. The role of double-stranded RNA in the induction of the acute-phase response in an abortive influenza virus infection model. J. Infect. Dis. 166: 1266-1275.

Hong, L., L. Imeri, M.R. Opp, A.E. Postlethwaite, J.M. Seyer, and J.M. Krueger. 1993. Intercellular adhesion molecule-1 expression induced by interleukin (IL)-1b or an IL-1b fragment is blocked by an IL-1 receptor antagonist and a soluble IL-1 receptor. J. Neuroimmunol. 44: 163-170.

Toth, L.A., E.A. Tolley, and J.M. Krueger. 1993. Sleep as a prognostic indicator during infectious disease in rabbits. Proc. Soc. Exper. Biol. Med. 203: 179-192.

Krueger, J.M., and F. Obál, Jr. 1993. Growth hormone releasing hormone and interleukin-1 in sleep regulation. FASEB J. 7: 645-652.

Krueger, J.M., and F. Obál, Jr. 1993. A neuronal group theory of sleep function. J. Sleep Res. 2: 63-69.

Imeri, L., M.R. Opp, and J.M. Krueger. 1993. An IL-1 receptor and an IL-1 receptor antagonist attenuate muramyl dipeptide- and IL-1-induced sleep and fever. Am. J. Physiol. 265: R907-R913.

Krueger, J.M. 1993. Chemistry of Sleep, Sleep Factors. In: Encyclopedia of Sleep and Dreaming. M. Carskadon (ed.). MacMillian Publishing Company: New York, NY; pp. 108-109.

Krueger, J.M., L. Kapás, M. Kimura-Takeuchi, and M.R. Opp. 1993. Somnogenic cytokines: Methods and overview. In: Methods in Neuroscience. Vol. 17, Part B: "Neurobiology of Cytokines". E.D. DeSouza (ed). Academic Press: Orlando, FL; pp. 111-129.

Kapás, L., F. Obál, Jr., and J.M. Krueger. 1993. Humoral regulation of sleep. In: International Review of Neurobiology. Vol. 35. R.J. Bradley and R.A. Harris (eds.). Academic Press; pp. 131-160.

Krueger, J.M., M.R. Opp, L. Kapás, and F. Obál, Jr. 1993. Interleukin-1 in sleep regulation. In: Sleep-Wakefulness. V. Mohan Kumar, H.N. Mallick, and U. Nayar, (eds.). Wiley Eastern Ltd.: New Delhi, INDIA; pp. 11-15.

Toth, L.A., M. Kimura-Takeuchi, and J.M. Krueger. 1993. Hypersomnia during infectious disease. In: Sleep-Wakefulness. V. Mohan Kuman, H.N. Mallick, and U. Nayar, (eds.). Wiley Eastern Ltd.: New Delhi, INDIA; pp. 155-159.

Obál, Jr., F., J. Fang, L. Payne, and J.M. Krueger. 1993. Interactions between interleukin-1 and growth hormone-releasing hormone in promoting sleep. In: Environment and Physiology. B.N. Mallick and R. Singh (eds.). Narosa Publishing House: New Delhi, INDIA; pp. 180-185.

Krueger, J.M., L. Toth and C. Shapiro. 1993. Sleep, the immune response and infectious disease. In: ABC of Sleep Disorders. BMJ Publishing Group: London, UNITED KINGDOM; pp. 55-58.

Payne, L., F. Obál, Jr., and J.M. Krueger. 1993. Hypothalamic releasing hormones mediating the effects of interleukin-1 on sleep. J. Cell. Biochem. 53: 309-313.

Kapás, L., M. Shibata, M. Kimura, and J.M. Krueger. 1994. Inhibition of nitric oxide synthesis suppresses sleep in rabbits. Am. J. Physiol. 266: R151-R157.

Opp, M.R., and J.M. Krueger. 1994. Anti-interleukin-1b reduces sleep and sleep rebound after sleep deprivation in rats. Am. J. Physiol. 266: R688-R695.

Opp, M.R., and J.M. Krueger. 1994. Interleukin-1 is involved in responses to sleep deprivation in the rabbit. Brain Res. 639: 57-65.

Johannsen, L., F. Obál, Jr., L. Kapás, V. Kovalzon, and J.M. Krueger. 1994. Somnogenic activity of muramyl peptide-derived immune adjuvants. Int. J. Immunopharm. 16: 109-116.

Toth, L.A., E.A. Tolley, R. Broady, B. Blakely, and J.M. Krueger. 1994. Sleep during experimental trypanosomiasis in rabbits. Proc. Soc. Exper. Med. Biol. 205: 174-181.

Krueger, J.M., L.A. Toth, R. Floyd, J. Fang, L. Kapás, S. Bredow, and F. Obál, Jr. 1994. Sleep, microbes and cytokines. Neuroimmunomodulation 1: 100-109.

Kimura, M., J.A. Majde, L.A. Toth, M.R. Opp, and J.M. Krueger. 1994. Somnogenic effects of rabbit and human recombinant interferons in rabbits. Am. J. Physiol. 267: R53-R61.

Obál, Jr., F., L. Payne, B. Kacsóh, M. Opp, L. Kapás, C.E. Grosvenor, and J.M. Krueger. 1994. Involvement of prolactin in the REM sleep-promoting activity of systemic vasoactive intestinal peptide (VIP). Brain Res. 645: 143-149.

Krueger, J.M., and L.A. Toth. 1994. Cytokines as regulators of sleep. Ann. N.Y. Acad. Sci. 739: 299-310.

Krueger, J.M., and F. Obál, Jr. 1994. Sleep Factors. In: Sleep and Breathing. N.A. Saunders and C.E. Sullivan (eds.). Marcel Dekker, Inc.: New York, NY; pp. 79-112.

Krueger, J.M., and V.M. Kovalzon. 1994. Sleep: modern thoughts on an ancient enigma. Sci. Humanity (in Russian); pp. 50-57.

Kimura, M., L.A. Toth, H. Agostini, A.B. Cady, J.A. Majde, and J.M. Krueger. 1994. Comparison of acute-phase responses induced in rabbits by the lipopolysaccharide of endotoxin and the double-stranded RNA polyriboinosinic:poly-ribocytidylic acid. Am. J. Physiol. 267: R1596-R1606.

Bredow, S., B. Kacsóh, F. Obál, Jr., J. Fang, and J.M. Krueger. 1994. Increase of prolactin mRNA in the rat hypothalamus after intracerebroventricular injection of VIP or PACAP. Brain Res. 660: 301-308.

Kapás, L., J. Fang, and J.M. Krueger. 1994. Inhibition of nitric oxide synthesis inhibits rat sleep. Brain Res. 664: 189-196.

Krueger, J.M., and L.A. Toth. 1994. Cytokines and Sleep Mechanisms. In: Advances in Psychoneuroimmunology. J. Szelenyi and I. Berczi, (eds.). Plenum Press: New York, NY; pp. 161-172.

Krueger, J.M., and J.A. Majde. 1994. Microbial products and cytokines in sleep and fever regulation. Crit. Rev. in Immunol. 14: 355-379.

Krueger, J.M., and F. Obál, Jr. 1994. Sleep substances: an unavoidable fact of neurobiology. World Fed. Sleep Res. Soc. Newslett. 3: 10-15.

Kovalzon, V.M., F. Obál, Jr., L. Johannsen, J.M. Krueger, and T.M. Andronova. 1994. The muramyl peptides and sleep. Sechenov Physiol. J. (in Russian) 80: 44-50.

Krueger, J.M., F. Obál, Jr., L. Kapás, and J. Fang. 1995. Brain organization and sleep function. Beh. Brain Res. 69: 177-185.

Obál, Jr., F., J. Fang, L.C. Payne, and J.M. Krueger. 1995. Growth hormone-releasing hormone (GHRH) mediates the sleep promoting activity of interleukin-1 (IL1) in rats. Neuroendocrinology 61: 559-565.

Kapás, L., M. Shibata, and J.M. Krueger. 1995. The role of cytokines in sleep, fever and anorexia. In: Human Cytokines: Their Role in Disease and Therapy. B.B. Aggarwal and R.K. Puri (eds.). Blackwell Scientific Publications, Inc.: Cambridge, MA; pp. 305-314.

Krueger, J.M. 1995. Sleep and the immune system. Sleep Med. Rev. Jan/Feb III; pp. 1-2.

Krueger, J.M., and M.L. Karnovsky. 1995. Sleep as a neuroimmune phenomenon: a brief historical perspective. Adv. Neuroimmunol. 5: 5-12.

Knefati, M., C. Somogyi, L. Kapás, T. Bourcier, and J.M. Krueger. 1995. Acidic fibroblast growth factor (FGF) but not basic FGF induces sleep and fever in rabbits. Am. J. Physiol. 269: R87-R91.

Krueger, J.M., and J.A. Majde. 1995. Cytokines and sleep. Int. Arch. Allergy Immunol. 106: 97-100.

Krueger, J.M., S. Takahashi, L. Kapás, S. Bredow, R. Roky, J. Fang, R. Floyd, K. Renegar, N. Guha-Thakurta, S. Novitsky, and F. Obál, Jr. 1995. Cytokines in sleep regulation. Adv. in Neuroimmunol. 5: 171-188.

Fang, J., L. Payne, and J.M. Krueger. 1995. Pituitary adenylate cyclase activating polypeptide enhances rapid eye movement sleep in rats. Brain Res. 686: 23-28.

Roky, R., F. Obál, Jr., J.L. Valatx, S. Bredow, J. Fang, L. P. Pagano, and J.M. Krueger. 1995. Prolactin and rapid eye movement sleep. Sleep 18: 536-542.

Takahashi, S., L. Kapás, J. Fang, and J.M. Krueger. 1995. Anti-tumor necrosis factor antibody suppresses sleep in rats and rabbits. Brain Res. 690: 241-244.

Fang, J., C.K. Sanborn, K.B. Renegar, J.A. Majde, and J.M. Krueger. 1995. Influenza viral infections enhance sleep in mice. Proc. Soc. Exp. Med. Biol. 210: 242-252.

Toth, L.A., and J.M. Krueger. 1995. Lighting conditions alter Candida albicans-induced sleep responses. Am. J. Physiol. 269: R1441-R1447.

Takahashi, S., D. Tooley, L. Kapás, J. Fang, J.M. Seyer, and J.M. Krueger. 1995. Inhibition of tumor necrosis factor suppresses sleep in rabbits. Pflügers Arch. 431: 155-160.

Kapás, L., and J.M. Krueger. 1996. Interactive effects of cytokines in the brain: sleep, fever and anorexia. In: The Physiology of Immunity. J.A. Marsh and M.D. Kendall (eds.). CRC Press: Boca Raton, FL; pp. 157-167.

Obál, Jr., F., R. Floyd, L. Kapás, B. Bodosi, and J.M. Krueger. 1996. Effects of systemic GHRH on sleep in intact and hypophysectomized rats. Am. J. Physiol. 270: E230-E237.

Ayers, N.A., L. Kapás, and J.M. Krueger. 1996. Circadian variation of nitric oxide synthase activity and cytosolic protein levels in rat brain. Brain Res. 707: 127-130.

Kapás, L., F. Obál, Jr., A.A. Book, J.B. Schweitzer, R.G. Wiley, and J.M. Krueger. 1996. The Effects of immunolesions of nerve growth factor-receptive neurons by 192-IgG saporin on sleep. Brain Res. 712: 53-59.

Takahashi, S., L. Kapás, J.M. Seyer, Y. Wang, and J.M. Krueger. 1996. Inhibition of tumor necrosis factor attenuates physiological sleep in rabbits. NeuroReport 7: 642-646.

Fincher, E.F., L. Johannsen, L. Kapás, S. Takahashi, and J.M. Krueger. 1996. Microglia digest Staphylococcus aureus into low molecular weight biologically active compounds. Am. J. Physiol. 271: R149-R156.

Takahashi, S., L. Kapás, J. Fang, Y. Wang, J.M. Seyer, and J.M. Krueger. 1996. An interleukin-1 receptor fragment inhibits spontaneous sleep and muramyl dipeptide-induced sleep in rabbits. Am. J. Physiol. 271: R101-R108.

Shibata, M., H. Parfenova, S.L. Zuckerman, J.M. Seyer, J.M. Krueger, and C.W. Leffler. 1996. Interleukin-1b peptides induce cerebral pial arteriolar dilation in anesthetized newborn pigs. Am. J. Physiol. 270: R1044-R1050.

Fang, J., D. Tooley, C. Gatewood, K.B. Renegar, J.A. Majde and J.M. Krueger. 1996. Differential effects of total and upper airway influenza viral infection on sleep in mice. Sleep 19: 337-342.

Krueger, J.M., S. Takahashi, J. Fang. 1996. Cytokines as Regulators of Sleep. In: Physiological Basis of Occupational Heath: Stressful Environments. K. Shiraki and M.K. Youref (eds.). SPB Academic Publishing: Amsterdam, NETHERLANDS; pp. 267-278.

Takahashi, S., L. Kapás and J.M. Krueger. 1996. A tumor necrosis factor (TNF) receptor fragment attenuates TNF-a and muramyl dipeptide-induced sleep and fever in rabbits. J. Sleep Res. 5: 106-114.

Fincher, E.F., M.J. Pabst, and J.M. Krueger. 1996. Neutrophils but not monocytes or microglia degrade interleukin-1. Neuroimmunomodulation 3: 82-86.

Krueger, J.M. 1996. Cytokine involvement in sleep responses to infection and physiological sleep. In: Cytokines in the Nervous System. N.J. Rothwell (ed.). Landes Publishing: Austin, TX; pp. 41-71.

Bredow, S., P. Taishi, F. Obál, Jr., N. Guha-Thakurta, and J.M. Krueger. 1996. Hypothalamic growth hormone-releasing hormone (GHRH) mRNA varies across the day in rats. NeuroReport 7: 2501-2505.

Kapás, L. and J.M. Krueger. 1996. Nitric oxide donors SIN-1 and SNAP promote non-rapid eye movement sleep in rats. Brain Res. Bull. 41: 293-298.

Zhang, J., F. Obál, Jr., J. Fang, B.J. Collins, and J.M. Krueger. 1996. Non-rapid eye movement sleep is suppressed in transgenic mice with a deficiency in the somatotropic system. Neurosci. Lett. 220: 97-100.

Krueger, J.M., and S. Takahashi. 1997. Thermoregulation and sleep: Closely linked but separable. Ann. N.Y. Acad. Sci. 813: 281-286.

Krueger, J.M., and F. Obál, Jr. 1997. Sleep regulatory substances. In: Monographs in Clinical Neuroscience. W.J. Schwartz. (ed.). Karger: Basel; 15: 175-194.

Ayers, N.A., L. Kapás and J.M. Krueger. 1997. The inhibitory effects of Nw -nitro-L-arginine methyl ester on nitric oxide synthase activity vary among brain regions in vivo but not in vitro. Neurochem. Res. 22: 81-86.

Takahashi, S., and J.M. Krueger. 1997. Inhibition of tumor necrosis factor prevents warming-induced sleep responses in rabbits. Am. J. Physiol. 41: R1325-R1329.

Taishi, P., S. Bredow, N. Guha-Thakurta, F. Obál, Jr., and J.M. Krueger. 1997. Diurnal variations of interleukin-1 beta mRNA and beta actin mRNA in rat brain.. J. Neuroimmunol. 75: 69-74.

Krueger, J.M., and J. Fang. 1997. Cytokines in sleep regulation. In: Sleep and Sleep Disorders: From Molecule to Behavior. O. Hayaishi and S. Inoue (eds.). Academic Press; pp. 261-277.

Obál, Jr., F., B. Bodosi, A. Szilagyi, B. Kacsóh, and J.M. Krueger. 1997. Antiserum to growth hormone suppresses sleep in the rat. Neuroendocrinology 66: 9-16.

Obál, Jr., F., B. Kacsóh, S. Bredow, N. Guha-Thakurta, and J.M. Krueger. 1997. Sleep in rats rendered chronically hyperprolactinemic with anterior pituitary grafts. . Brain Res. 755: 130-136.

Floyd, R.A., and J.M. Krueger. 1997. Diurnal variations of TNFa in the rat brain. NeuroReport 8: 915-918.

Krueger, J.M. 1997. Sleep and Immune Function,. Karger Gazette (April), No. 61: 6-8.

Takahashi, S., J. Fang, L. Kapás, Y. Wang, and J.M. Krueger. 1997.  Inhibition of brain interleukin-1 attenuates sleep rebound after sleep deprivation in rabbits.. Am. J. Physiol. 273: R677-R682.

Fang, J., Y. Wang, and J.M. Krueger. 1997. Mice lacking the TNF 55-kD receptor fail to sleep more after TNFa treatment. J. Neurosci. 17: 5949-5955.

Beranek, L., F. Obál, Jr., P. Taishi, B. Bodosi, F. Laczi, and J.M. Krueger. 1997. Changes in rat sleep after single and repeated injections of the long-acting somatostatin analog, octreotide. Am. J. Physiol. 42: R1484-R1491.

Hansen, M.K. and J.M. Krueger. 1997. Subdiaphragmatic vagotomy blocks the sleep and fever-promoting effects of interleukin-1b . Am. J. Physiol. 273: R1246-R1253.

Bredow, S., P. Taishi, N. Guha-Thakurta, F. Obál, Jr., and J.M. Krueger. 1997. Diurnal variations of tumor necrosis factor-a mRNA and a -tubulin mRNA in rat brain. J. NeuroImmunoMod. 4: 84-90.

Chen, Z., and J.M. Krueger. 1998. Sleep Regulatory substances: Changes in mRNA expression linked to sleep. In: Molecular Regulation of Conscious States. R. Lydic (ed.). CRC Press: Boca Raton, FL; pp. 33-44.

Hansen, M., L. Kapás, J. Fang, and J.M. Krueger. 1998. Cafeteria diet-induced sleep is blocked by subdiaphragmatic vagotomy in rats. Am. J. Physiol. 274: R168-R174.

Kapás, L., M.K. Hansen, H.-Y. Chang, and J.M. Krueger. 1998. Vagotomy attenuates but does not prevent somnogenic and febrile effects of lipopolysaccharide in rats. Am. J. Physiol. 274: R406-R411.

Fang, J., Y. Wang, and J.M. Krueger. 1998. The effects of interleukin-1b on sleep are mediated by the type I receptor. Am. J. Physiol. 274: R655-R660.

Renegar, K.B., R. Floyd, and J.M. Krueger. 1998. Effect of sleep deprivation on serum influenza-specific IgG. Sleep. 21: 19-24.

Kimura, M., L. Kapás, and J.M. Krueger. 1998. Oxidized glutathione promotes sleep in rabbits. Brain Res. Bull. 45: 545-548.

Obál, Jr., F., L. Kapás, B. Bodosi, and J.M. Krueger. 1998. Changes in sleep in response to intracerebral injection of insulin-like growth factor-1 (IGF-1) in the rat. Sleep Res. Online 2: 87-91.

Hansen, M.K., P. Taishi, Z. Chen and J.M. Krueger. 1998. Vagotomy blocks the induction of interleukin-1b mRNA in the brain of rats in response to systemic interleukin-1b . J. Neurosci. 18: 2247-2253.

Kushikata, T., S. Takahashi, Y. Wang, J. Fang and J.M. Krueger. 1998. An interleukin-1 receptor fragment blocks ambient temperature-induced increases in brain temperature but not sleep in rabbits. Neurosci. Lett. 244: 125-128.

Hansen, M.K., P. Taishi, Z. Chen and J.M. Krueger. 1998. Cafeteria-feeding induces interleukin-1b mRNA expression in rat liver and brain. Am. J. Physiol. 43: R1734-R1739.

Renegar, K.B., R.A. Floyd, and J.M. Krueger. 1998. Effects of short-term sleep deprivation on murine immunity to influenza virus in young adult and senescent mice. Sleep 21: 241-248.

Krueger, J.M., J. Fang, M.K. Hansen, J. Zhang, and F. Obál, Jr. 1998. Humoral regulation of sleep. News Physiol. Sci. 13: 189-194.

Kushikata, T., J. Fang, Z. Chen, Y. Wang, and J.M. Krueger. 1998. Epidermal growth factor (EGF) enhances spontaneous sleep in rabbits. Am. J. Physiol. 275: R509-R514.

Obál, Jr., F., L. Kapás, and J.M. Krueger. 1998. Albumin enhances sleep in the young rat. Physiol. Behav. 64: 261-266.

Hansen, M.K., and J.M. Krueger. 1998. Subdiaphragmatic vagotomy does not block sleep deprivation-induced sleep in rats. Physiol. Behav. 64: 361-365.

Taishi, P., Z. Chen, F. Obál, Jr., J. Zhang, M. Hansen, J. Fang, and J.M. Krueger. 1998. Sleep-associated changes in interleukin-1b mRNA in the brain. J. Interferon Cytokine Res. 18: 793-798.

Krueger, J.M., J. Fang, P. Taishi, Z. Chen, T. Kashikata, J. Gardi. 1998. Sleep: a physiological role for IL1b and TNFa . Ann. New York Acad. Sci. 856: 148-159.

Kushikata, T., J. Fang, Y. Wang, and J.M. Krueger. 1998. Interleukin-4 inhibits spontaneous sleep in rabbits. Am. J. Physiol. 275: R1185-R1191.

Krueger, J.M. 1998. Animal models of sleep. J. Musculoskeletal Pain 6: 87-92.

Majde, J.A., N. Guha-Thakurta, Z. Chen, S. Bredow, and J.M. Krueger. 1998. Spontaneous release of stable viral double-stranded RNA into the extracellular medium by influenza virus-infected MDCK epithelial cells: implications for the viral acute phase response. Arch. of Virol. 143: 2371-2380.

Zhang, J., Z. Chen, P. Taishi, F. Obál, Jr., J. Fang, and J.M. Krueger. 1998. Sleep deprivation increases rat hypothalamic growth hormone-releasing hormone mRNA. Am. J. Physiology 275: R1755-R1761.

Krueger, J.M. and J. Fang. 1999. Cytokines and sleep regulation. In: Handbook of Behavioral State Control. R. Lydic and H.A. Baghdoyan (eds.). CRC Press: Boca Raton, FL; pp. 609-622.

Fang, J., S. Bredow, P. Taishi, J.A. Majde, and J.M. Krueger. 1999. Synthetic influenza viral double-stranded RNA induces an acute phase response in rabbits. J. Med. Virol. 57: 198-203.

Zhang, J., F. Obál, Jr., T. Zheng, J. Fang, P. Taishi and J.M. Krueger. 1999. Intrapreoptic microinjection of GHRH or its antagonist alters sleep in rats. J. Neurosci. 19: 2187-2194.

Obál, Jr., F., and J.M. Krueger. 1999. Hormones and REM sleep. In: Rapid Eye Movement Sleep. B.N. Mallick and S. Inoue (eds.) Narosa Publishers: New Delhi, INDIA; pp. 233-247.

Takahashi, S., L. Kapás, J. Fang, and J.M. Krueger. 1999. Somnogenic relationships between tumor necrosis factor and interleukin-1. Am. J. Physiol. 276: R1132-R1140.

Kushikata, T., J. Fang, and J.M. Krueger. 1999. Brain-derived neurotrophic factor enhances spontaneous sleep in rats and rabbits. Am. J. Physiol. 276: R1334-1338.

Takahashi, S., and J.M. Krueger. 1999. Nerve growth factor enhances sleep in rabbits. Neurosci. Lett. 264: 149-152.

Krueger, J.M., R.A. Floyd, and J. Fang. 1999. Relationships between sleep and immune function. In: Regulation of Sleep and Circadian Rhythms. F.W. Turek and P.C. Zee (eds.). Marcel Dekker, Inc.: New York, NY; pp. 427-464.

Chen, Z., J. Gardi, T. Kushikata, J. Fang, and J.M. Krueger. 1999. Nuclear factor kappa B-like activity increases in murine cerebral cortex after sleep deprivation. Am. J. Physiol. 45: R1812-R1818.

Krueger, J.M., F. Obál, Jr., and J. Fang. 1999. Humoral regulation of physiological sleep; cytokines and GHRH. J. Sleep Res. 8(Supp. 1): 53-59.

Obál, Jr., F., L. Kapás, J. Gardi, P. Taishi, B. Bodosi, and J.M. Krueger. 1999. Insulin-like growth factor-1 (IGF-1) induced inhibition of growth hormone secretion is associated with sleep suppression. Brain Res. 818: 267-274.

Krueger, J.M., F. Obál, Jr., and J. Fang. 1999. Why we sleep. Sleep Med. Rev. 3: 119-129.

Obál, Jr., F., and J.M. Krueger. 2000. Hormones, cytokines and sleep. In: Coping with the Environment Neural and Endocrine Mechanisms: Handbook of Physiology. B.S. McEwen (ed.). Oxford University Press; Chapt. 16, pp. 331-349.

Krueger, J.M. The sleep-wake cycle and its regulation. In: Principles of Medical Biology. E. Bittar (ed.). J.A. II. Press, Inc.: Greenwich (In press).

Krueger, J.M., and J. Fang. 2000. Sleep and host defense. In: Principles and Practice of Sleep Medicine. 3rd edition. M.H. Kryger, T. Roth and W. Dement (eds.). W.B. Saunders Co.: Orlando, FL; pp. 255-265.

Krueger, J.M. 1998. Neurochemistry of sleep regulation. Le Cahiers du Médecin 13: 14-15.

Pabst, M.J., S. Beranova, and J.M. Krueger. 1999. A review of the effects of muramyl pep-tides on macrophages, monokines and sleep. Neuroimmunomodulation 6: 261-283.

Kushikata, T., F. Fang, and J.M. Krueger. 1999. Interleukin-10 inhibits spontaneous sleep in rabbits. J. Interferon Cytokine Res. 19: 1025-1030.

Hansen, M.K., and J.M. Krueger. 1999. Kupffer cell depletion with gadolinium chloride prevents cafeteria diet-induced sleep in rats. Sleep 22:707-715.

Roky, R., L. Kapás, P. Taishi, J. Fang, and J.M. Krueger. 1999. Food restriction alters the diurnal distribution of sleep in rats. Physiol. Behav. 67: 697-703.

Gardi, J., F. Obál, Jr., J. Fang, J. Zhang, and J.M. Krueger. 1999. Diurnal variations and sleep-deprivation-induced changes in rat hypothalamic GHRH and somatostatin contents. Am. J. Physiol. 46: R1339-R1344.

Beranek, L., I. Hadju, J. Gardi, P. Taishi, F. Obál, Jr., and J.M. Krueger. 1999. Central administration of the somatostatin analog octreotide induces captopril-insensitive sleep responses. Am. J. Physiol. 46: R1297-R1304.

Krueger, J.M., J. Fang and F. Obál, Jr. 2000. La solitude nocturne des neurons. La Recherche. A3, April 2000, pp. 26-27.

Krueger, J.M. 2000. Cytokines and growth factors in sleep regulation. In: HFSP Workshop 8, The Regulation of Sleep. pp. 122-131.

Krueger, J.M., J. Fang, J.A. Majde. 2001. Sleep in health and disease. In: Psychoneuroimmunology, 3rd edition. B. Ader, D. Felton, N. Cohen (eds.). Academic Press. pp. 667-685.

Hajdu, I., F. Obál, Jr., J. Gardi, F. Laczi, and J.M. Krueger. 2000. Octreotide-induced drinking, vasopressin and pressure responses: involvement of central angiotensin and acetylcholine. Am. J. Physiol. 279: R271-R277.

Kubota, T., T. Kushikata, J. Fang, and J.M. Krueger. 2000. A nuclear factor kappa b (NFkB) inhibitor peptide inhibits spontaneous and interleukin-1b -induced sleep. Am. J. Physiol. 279: R404-R413.

Kubota, T., J. Fang, T. Kushikata, and J.M. Krueger. 2000. Interleukin 13 and transforming growth factor-b 1 inhibit spontaneous sleep in rabbits. Am. J. Physiol. 279: R786-R792.

Bodosi, B., F. Obál, Jr., J. Gardi, J. Komlódi, and J.M. Krueger. 2000. Ether stress induces increases in REM sleep in the rat: possible role of prolactin. Am. J. Physiol. 279: R1590-R1598.

Krueger, J.M., F. Obál Jr., J. Fang, T. Kubota, and P. Taishi. 2001. The role of cytokines in sleep regulation. Ann. NY Acad. Sci. 933: 211-221.

Renegar, K.B., D. Crouse, R.A. Floyd, and J.M. Krueger. 2000. Progression of influenza viral infection through the respiratory tract: the protective role of short-term sleep-deprivation. Sleep 23: 859-863.

Rehman, A., P. Taishi, J. Fang, J.A. Majde, and J.M. Krueger. 2001. The cloning of a rat peptidoglycan recognition protein (PGRP) and its induction in brain by sleep deprivation. Cytokine 13: 8-17.

Kubota, T., J. Fang, Z Guan, R.A. Brown and J.M. Krueger. 2001. Vagotomy attenuates tumor necrosis factor-a induced sleep and EEG delta activity. Am. J. Physiol. 280: R1213-1220.

Kushikata, T., T. Kubota, J. Fang, and J.M. Krueger. 2001. Glial cell line-derived neurotrophic factor (GDNF) promotes sleep in rats and rabbits. Am. J. Physiol. 280: R1001-R1006.

Obál, Jr., F., J. Fang, P. Taishi, B. Kacsoh, J. Gardi, and J.M. Krueger. 2001. Deficiency of growth hormone-releasing hormone signaling is associated with sleep alterations in the dwarf rat. J. Neurosci. 21: 2912-2918.

Churchill, L., P. Taishi, Z. Guan, L. Chen, J. Fang, and J.M. Krueger. 2001. Sleep modifies glutamate decarboxylase mRNA within the barrel cortex of rats after a mystacial whisker trim. Sleep 24: 261-266.

Obál, Jr., F., and J.M. Krueger. 2001. The somatotropic axis and sleep. Revue Neurologique 157: 5512-5515.

Krueger, J.M., and F. Obál, Jr. 2002. Function of sleep. In: Sleep Medicine. T. Lee-Choing, M. Carskadon and M. Sateia (eds.). Hanley & Belfus, Inc.: Philadelphia, PA; pp. 23-30.

Majde, J.A., and J.M. Krueger. Neuroimmunology of sleep. In: Textbook of Biological Psychiatry. H. D'haenen, J.A. den Boer, H. Westenberg and P. Willner (eds.). John Wiley & Sons, Ltd.: London, UNITED KINGDOM. 2002.

Kubota, T., R.A. Brown, J. Fang, and J.M. Krueger. 2001. Interleukin-15 and interleukin-2 enhance non-REM sleep in rabbits. Am. J. Physiol. 281: R1004-R1012.

Kubota, T., J. Fang, R.A. Brown, and J.M. Krueger. 2001. Interleukin-18 promotes sleep in rabbits and rats. Am. J. Physiol. 281: R828-R838.

Kubota, T., J.A. Majde, R.A. Brown and J.M. Krueger. 2001. Tumor necrosis factor receptor fragment attenuates interferon-g -induced non-REM sleep in rabbits. J. Neuroimmunol. 119: 192-198.

Gardi, J., J.M. Krueger, and R.C. Speth. 2001. Preparation and a simple one-step purification of [His1-mono-125I-tyr10, Nle27] - hGHRH (1-32)-NH2. J. Labeled Compounds Radiopharm. 44: 1-6.

Kubota, T., J. Fang, L.T. Meltzer, and J.M. Krueger. 2001. Pregabalin enhances non-REM sleep. J. Pharm. Exper. Ther. 299: 1095-1105.

Hajdu, I., F. Obál Jr., J. Fang, J.M. Krueger, and C.D. Rollo. 2002. Sleep of transgenic mice producing excess rat growth hormone. Am. J. Physiol. 282: R70-R76.

Gardi, J., E. Szentirmai, I. Hajdu, F. Obál, Jr., and J.M. Krueger. 2001. The somatostatin analog, octreotide, inhibits GHRH and stimulates angiotensin release in the rat hypothalamus. Neurosci. Lett. 315: 37-40.

Krueger, J.M., F. Obál Jr., J.W. Harding, J.W. Wright, and L. Churchill. Sleep modulation of the expression of plasticity markers. In: Sleep and Brain Plasticity. P. Maquet, R. Stickgold and C. Smith (eds.). Oxford University Press: Oxford, UNITED KINGDOM. (In press).

Kubota, T., A. De, R.A. Brown, S.M. Simasko, J.M. Krueger. 2002. Diurnal effects of acute and chronic administration of ethanol on sleep in rats. Alcohol. Clin. Exp. Res. 26: 1153-1161.

Gardi, J., R.C. Speth, P. Taishi, B. Kacsóh, F. Obál, Jr., and J.M. Krueger. 2002. Alterations in GHRH binding in the pituitary of adult dw/dw rats. Peptides 23: 1497-1502.

Gardi, J., P. Taishi, R. Speth, F. Obál Jr. and J.M. Krueger. 2002. Sleep loss alters hypothalamic growth hormone releasing hormone receptors. Neurosci. Lett. 320: 69-72.

Krueger, J.M., and L. Churchill. Cytokines in sleep regulation. 2003. In: Cytokine and Mental Health. A. Krontol (ed.). Kluwer Academic Publishers: New York, NY; pp 147-166.

Obál Jr., F., J. Alt, P. Taishi, J. Gardi, and J.M. Krueger. 2003. Sleep in mice with non-functional growth hormone (GH)-releasing hormone (GHRH) receptors: effects of GH, GHRH, ghrelin and the somatostatin analog (octreotide). Am. J. Physiol. 284: R131-R139.

Krueger, J.M.,
J.A. Majde, and F. Obál, Jr. 2003. Sleep in host defense. Brain Beh. Immunity 17: S41-S47.

Obál Jr., F., and J.M. Krueger. 2003. Biochemical regulation of sleep. Frontiers Biosci. 8: 520-550.

Krueger, J.M., and F. Obál, Jr. 2003. Sleep function. Frontiers Biosci. 8: 511-519.

Krueger, J.M., and J.A. Majde. 2003. Humoral links between sleep and the immune system – Research Issues. Ann. NY Acad. Sci. 992: 9-20.

Alt, J.A., F. Obál, Jr., T.R. Traynor, J. Gardi, J.A. Majde, and J.M. Krueger. 2003. Sleep responses to influenza viral infection in GHRH-receptor deficient mice. J. Appl. Physiol. 95: 460-468.

Chen, L., J.A. Majde, and J.M. Krueger. 2003. Spontaneous sleep in mice with targeted disruptions of neuronal or inducible nitric oxide synthase genes. Brain Res. 973: 214-222.

Yoshida, H., T. Kubota, and J.M. Krueger. 2003. A cyclooxygenase-2 inhibitor attenuates spontaneous and TNF?-induced non-rapid eye movement sleep in rabbits. Am. J. Physiol. 285: R99-R109.

De, A., J.M. Krueger, and S.M. Simasko. 2003. Tumor necrosis factor ? increases cytosolic Ca++ responses to AMPA and KCl in primary cultures of rat hippocampal neurons. Brain Res. 981: 133-142.

Kushikata, T., T. Kubota, J. Fang, and J.M. Krueger. 2003. Neutrophin 3 and 4 enhance spontaneous sleep in rabbits. Neurosci. Lett. 346: 161-164.

Garcia-Garcia, F., and J.M. Krueger. 2003. Intracerebroventricular injection of erythropoietin enhances sleep in the rat. Brain Res. Bull. 61: 541-546.

Cearley, C., L. Churchill, and J.M. Krueger. 2003. Time of day differences in IL1? and TNF? mRNA levels in specific regions of brain. Neurosci. Lett. 352: 64-66.

Hajdu, I., E. Szentirmai, F. Obál, Jr., and J.M. Krueger. 2003. Different brain structures mediate drinking and sleep suppression elicited by the somatostatin analog, octreotide, in rats. Brain Res. 994: 115-123.

Krueger, J.M., F. Obál Jr., J.W. Harding, J.W. Wright, and L. Churchill. 2003. Sleep modulation of the expression of plasticity markers. In: Sleep and Brain Plasticity. P. Maquet, R. Stickgold and C. Smith (eds.). Oxford University Press: Oxford, UNITED KINGDOM; pp 363-376.

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