Program in Genomics
Kelly A. Brayton and Douglas R. Call
- Encourage interdisciplinary collaborations and graduate and
post-graduate research opportunities.
- Examine genetic
diversity as it relates to differential survivorship and virulence.
Identify mechanisms responsible for generating genetic diversity.
Develop new tools for diagnostics and strategies for pathogen
control and intervention
Microarrays - Douglas R.
- Whole genome comparative analysis of
Anaplasma marginale strains
- Genome sequences for attenuated and virulent
- Genome sequences for Mannheimia
- Optical mapping of EHEC genotypes
- Developed mixed-genome and mixed-plasmid
microarrays to study molecular epidemiology
of food-borne pathogens and antibiotic
- Developing arrays suitable for simultaneous
detection of multiple pathogens.
Thomas E. Besser
Kelly A. Brayton
Douglas R. Call
Donald P. Knowles
Audrey O.T. Lau
Terry F. McElwain
Guy H. Palmer
Example of genomic hybridizations for two
strains of L. monocytogenes (serotypes 1/2a, top
and 4b, bottom). Only a portion of the full
array is shown. Spots clearly visible indicate
presence of target. Missing spots are
attributable to absent or highly diverged
sequence (e.g., column 1, row 4).||
This Program receives support from the
National Institutes of Health (NIH) USDA-AFRI
USDA-ARS ADRU Microbial Genomics Initiative
USDA Northwest Aquaculture Initiative
WSU College of Veterinary Medicine Agricultural Animal Health