College of Veterinary Medicine

Research in Veterinary Clinical Sciences

Currently Enrolling Candidates for a Non-Invasive Clinical Trial for Dogs with Osteoarthritis


The Comparative Orthopedic Research Laboratory at Washington State University is conducting a study designed to evaluate the effectiveness, safety, and oral acceptability of a flavored tablet product for dogs diagnosed with osteoarthritis of the shoulder, hip, knee, or elbow joint. The investigational veterinary product is a member of a class of products known as non-steroidal anti-inflammatory drugs (NSAIDs) that are used to control pain and inflammation.  This product is approved for dogs in Europe, but not in the U.S.  Enrollees in the study will need to bring their dog to the VTH clinic four separate times over an approximate 5-week period.

Benefits

The costs of all study procedures, including the study’s required radiographs (and associated sedatives if needed), office visits, and laboratory tests are provided free of charge if dog is deemed eligible for enrollment.

There will be a financial incentive to be awarded to the client upon completion of the study, if all requirements are met.

Inclusion Criteria

  • Age: greater than or equal to 6 weeks of age. 
  • Patient weight: 15-80kg (33-176lb)
  • Behavior: non-fractious.
  • Absence of concurrent orthopedic, neurological, or uncontrolled systemic disorders.
  • Must not have had orthopedic surgery within the last 3 months.
  • Dog does not exhibit gross instability of stifle joint (ruptured cruciate ligament)
  • Must be off of corticosteroids for 30 days prior to the first visit (90 days for intra-articular).
  • Must be off of NSAIDS 14 days prior to the first visit.
  • Must be off of opioids, gabapentin or herbal supplements for pain relief at least 2 days before the first visit.
  • If on glucosamine or chondroitin, must have been on for at least 30 days before the first visit.
  • Client must agree to administer treatments and keep a daily log.
  • No history of adverse reactions to opioids, NSAIDS, or Nutraceutical products.


For more information please contact Nicole Kuhn CORL manager at 509-335-7747 or Email nkuhn@vetmed.wsu.edu

Last Edited: Jul 01, 2013 9:35 AM


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