CD99R CD99R (epitope restricted to a subset of CD99 molecules), CD99 mAb restricted, E2
Molecule TypeAntigen ExpressionMolecular Weight
Min / Max
Non-lineage Restricted Molecule
Type 1 glycoprotein
T Cell
NK Cell
Myeloid Cell
Thymocyte
32 / 32

Expression
CD99R is expressed on myeloid, NK and double positive thymocytes and T cells.

Structure
MOLECULAR FAMILY NAME: Belongs to the mucin family.

CD99R is an epitope restricted to a subset of CD99 molecule.

MOLECULAR MASS

POST-TRANSCRIPTIONAL MODIFICATION: No information.

POST-TRANSLATIONAL MODIFICATION: No information.

 



Ligands
LIGANDS AND MOLECULES ASSOCIATED WITH CD99R: No information.

Function
CD99R is an isoform of CD99 and modulates T cell adhesion and induces apoptosis of double-positive thymocytes.  CD99R antibodies do not induce the cellular responses seen with CD99 antibodies.

BIOCHEMICAL ACTIVITY: No information.

DISEASE RELEVANCE AND FUNCTION OF CD99R IN INTACT ANIMAL: No information.


Comments
MOLECULAR INTERACTIONS
PROTEINS AND DNA ELEMENTS WHICH REGULATE TRANSCRIPTION OF CD99R: No information.

SUBSTRATES: No information.

ENZYMES WHICH MODIFY CD99R: No information.


Database accession numbers
AnimalPIRSWISSPROTEMGBL/GENBANK
 
Antibodies

Revised June 25, 2008


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