|CD15su||Sulphated CD15, 6' sulfated Lewis X|
|Molecule Type||Antigen Expression||Molecular Weight|
Min / Max
|Non-lineage Restricted Molecule|
|CD15su is expressed widely on neutrophils, basophils, mature granulocytes, monocytes, NK cells and T lymphocytes but expression on lymphocytes is variable depending on the antibodies used for detection. Expression is present on immature bone marrow cells and on endothelial cells of high endothelium (HEV) of peripheral lymph nodes. CD15su is expressed on myelomonocytic leukemia cells and on adenocarinomas.|
|MOLECULAR FAMILY NAME: Belongs to the carbohydrate family.|
POST-TRANSCRIPTIONAL MODIFICATION: No information.
POST-TRANSLATIONAL MODIFICATION: No information.
|LIGANDS AND MOLECULES ASSOCIATED WITH CD15su|
CD15su appears to act as a coreceptor for CD62L (L-selectin).
|CD15su form is the strongest binding partner for CD62 L-selectin. CD15su is involved with different carbohydrate to carbohydrate cell adhesion.|
BIOCHEMICAL ACTIVITY: No information.
DISEASE RELEVANCE AND FUNCTION OF CD15su IN INTACT ANIMAL: No information.
|MOLECULAR INTERACTIONS -|
PROTEINS AND DNA ELEMENTS WHICH REGULATE TRANSCRIPTION OF CD15su: No information.
SUBSTRATES: No information.
ENZYMES WHICH MODIFY CD15su: No information.
Database accession numbers
Revised June 25, 2008