CD45RA T200 Restricted, See antigen reactivity and See CD45
Molecule TypeAntigen ExpressionMolecular Weight
Min / Max
Non-lineage Restricted Molecule
Type 1 glycoprotein
B Cell
T Cell
Monocyte
Thymocyte
205 / 205
210 / 210

Expression
CD45RA is expressed on B cells, monocytes, resting/naive T cell subsets and medullary thymocytes.

Structure
MOLECULAR FAMILY NAME:

MOLECULAR MASS

POST-TRANSCRIPTIONAL MODIFICATION: No information.

POST-TRANSLATIONAL MODIFICATION: No information.


Ligands
LIGANDS AND MOLECULES ASSOCIATED WITH CD45RA: No information.

Function
CD45RA is a critical requirement for TCR and BCR mediated activation and is a possible requirement for receptor-mediated activation in other leukocytes.  CD45RA is an isoform of CD45 containing the A exon.

BIOCHEMICAL ACTIVITY: No information.

DISEASE RELEVANCE AND FUNCTION OF CD45RA IN INTACT ANIMAL: No information.

Comments
MOLECULAR INTERACTION-
PROTEINS AND DNA ELEMENTS WHICH REGULATE TRANSCRIPTION OF CD45RA: No information.

SUBSTRATES: No information.

ENZYMES WHICH MODIFY CD45RA: No information.


Database accession numbers
AnimalPIRSWISSPROTEMGBL/GENBANK
 
HumanEntrezgene 5788
Antibodies
4KB5   View Reactivity
5H9   View Reactivity
73B1   View Reactivity
ALB11   View Reactivity
CA4.1D3   View Reactivity
DBB42   View Reactivity
F8-11-13   View Reactivity
FB-11-13   View Reactivity
HI100   View Reactivity
MIL13   View Reactivity
PG167A   View Reactivity
PG96A   View Reactivity
PG97A   View Reactivity
PGB78A   View Reactivity

Revised June 25, 2008


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