CD45RC LCA (leukocyte common antigen), See antigen reactivity and See CD45
Molecule TypeAntigen ExpressionMolecular Weight
Min / Max
Non-lineage Restricted Molecule
Type 1 glycoprotein
B Cell
T Cell
Monocyte
NK Cell
Dendritic Cell
Thymocyte
220 / 220

Expression

CD45RC is expressed on B and NK cells, thymocytes, monocytes, dendritic cells and T cell subsets + CD4 and + CD8.



Structure
MOLECULAR FAMILY NAME:

MOLECULAR MASS

POST-TRANSCRIPTIONAL MODIFICATION: No information.

POST-TRANSLATIONAL MODIFICATION: No information.


Ligands
LIGANDS AND MOLECULES ASSOCIATED WITH CD45RC: No information.

Function
CD45RC is an isorform containing the C exon and is a critical requirement for TCR and BCR mediated activation and is a possible requirement for receptor-mediated activation in other leukocytes.

BIOCHEMICAL ACTIVITY: No information.

DISEASE RELEVANCE AND FUNCTION OF CD45RC IN INTACT ANIMAL: No imnformation.

Comments
MOLECULAR INTERACTION-
PROTEINS AND DNA ELEMENTS WHICH REGULATE TRANSCRIPTION OF CD45RC: No information.

SUBSTRATES: No information.

ENZYMES WHICH MODIFY CD45RC: No information.


Database accession numbers
AnimalPIRSWISSPROTEMGBL/GENBANK
 
HumanEntrezgene 5788
Antibodies
MIL15   View Reactivity
MIL5   View Reactivity
YTH80.103   View Reactivity

Revised June 25, 2008


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