|Molecule Type||Antigen Expression||Molecular Weight|
Min / Max
|Non-lineage Restricted Molecule|
Type 1 glycoprotein
|CD300e is expressed on the surface of monocytes, neutrophils and macrophages.|
|MOLECULAR FAMILY NAME: Belongs to the immunoglobulin gene family.|
CD300e is a single-pass type-1 205 aa integral glycoprotein. It contains an 12 aa signal sequence, a 44 aa extracellular domain which contains an Ig-like V-type domain and a potential N-glycosylation site, a transmembrane domain and a 10 aa cytoplasmic domain. CD300e is an activating receptor and is a newly identified member of the CMRF35 family within the Ig gene superfamily.
POST-TRANSCRIPTIONAL MODIFICATION: No information.
POST-TRANSLATIONAL MODIFICATION: No information.
|LIGANDS AND MOLECULE ASSOCIATED WITH CD300e: No information.|
|CD300e mediates activating signals by interacting with DAP12.|
BIOCHEMICAL ACTIVITY: No information.
DISEASE RELEVANCE AND FUNCTION OF CD300e INJ INTACT ANIMAL: No information.
PROTEINS AND DNA ELEMENTS WHICH REGULATE TRANSCRIPTION OF CD300e: No information.
SUBSTRATES: No information.
ENZYMES WHICH MODIFY CD300e: No information.
Database accession numbers
Revised June 25, 2008