|CLEC1A||CLEC1A (C-type lectin domain family member A), CLEC1|
|Molecule Type||Antigen Expression||Molecular Weight|
Min / Max
|Non-lineage Restricted Molecule|
Type 2 glycoprotein
CLEC1A is expressed by Northern blot analysis revealed expression was strong in placenta and lung, moderate expression in thymus and heart and weak in other tissues. RT-PCR analysis detected high levels of expression in dendritic cells activated TNF or CD154 but weak expression in monocytes and no expression in granulocytes and lymphocytes.
MOLECULAR FAMILY NAME: Belongs to the C-type lectin domain family.
|LIGANDS AND MOLECULES ASSOCIATED WITH CLEC1A: No information.|
|CLEC1A encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functionsm such as cell adhesion, cell-cell signaling, glycoprotein turnover and roles in inflammation and immune responses. The encoded protein may play a role in regulating dendritic cell function.|
BIOCHEMICAL ACTIVITY: No information.
DISEASE RELEVANCE AND FUNCTION OF CLEC1A IN INTACT ANIMAL: No information.
PROTEINS AND DNA ELEMENTS WHICH REGULATE TRANSCRIPTION OF CLEC1A: No information.
SUBSTRATES: No information.
ENZYMES WHICH MODIFY CLEC1A: No information.
Database accession numbers
Revised June 25, 2008