|LGALS4||LGALS4 (lectin, galactoside-binding soluble 4 [galection 4])|
|Molecule Type||Antigen Expression||Molecular Weight|
Min / Max
|Non-lineage Restricted Molecule|
LGALS4 is expressed in the small intestine, colon and rectum.
|MOLECULAR FAMILY NAME: Belongs to the galectin lectin family.|
LGALS4 is a 323 aa glycoprotein. It contains 2 homologous, approximately 150 aa carbohydrate recognition galectin domains and all amino acids are typically conserved in galectins.
POST-TRANSCRIPTIONAL MODIFICATION: No information.
POST-TRANSLATIONAL MODIFICATION: No information.
|LIGANDS AND MOLECULES ASSOCIATED WITH LGALS4: No information.|
|Galectins are a family of β-galactoside binding proteins implicated in modulating cell-cell and cell-matrix interactions and they bind lactose and a related range of sugars. LGALS4 may be involved in the assemby of adherens junctions.|
BIOCHEMICAL ACTIVITY: No information.
DISEASE RELEVANCE AND FUNCTION OF LGALS4 IN INTACT ANIMAL
LGALS4 is a S-type lectin that is strongly underexpressed in colorectal cancer.
PROTEINS AND DNA ELEMENTS WHICH REGULATE TRANSCRIPTION OF LGALS4: No information.
SUBSTRATES: No information.
ENZYMES WHICH MODIFY LGALS4: No information.
Database accession numbers
Revised June 25, 2008