|MS4A4A||MS4A4A (membrane spanning 4-domains subfamily A, member 4), CD20L1|
|Molecule Type||Antigen Expression||Molecular Weight|
Min / Max
|Non-lineage Restricted Molecule|
|MS4A4A is expressed on multiple hemopoietic cell lines and nonlymphoid tissues.|
|MOLECULAR FAMILY NAME: Belongs to the membrane spanning 4A family.|
MS4A4A ia a multi pass 205 aa glycoprotein. It contains a N-terminal extracellular domain, 4 highly conserved transmembrane domains and a C-terminal cytoplasmic domain which has a conserved phosphorylation site in the intracellular loop.
Alternative splicing yields 2 different isoforms but not all isoforms have been described.
POST-TRANSLATIONAL MODIFICATION: No information.
|LIGANDS AND MOLECULES ASSOCIATED WITH MS4A4A: No information.|
|MS4A4A encodes the membrane spanning 4A family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. MS4A4A may be involved in signal transduction as a component of a multimeric receptor complex.|
BIOCHEMICAL ACTIVITY: No information.
DISEASE RELEVANCE AND FUNCTION OF MS4A4A IN INTACT ANIMAL: No information.
PROTEINS AND DNA ELEMENTS WHICH REGULATE TRANSCRIPTION OF MS4A4A: No information.
SUBSTRATES: No information.
ENZYMES WHICH MODIFY MS4A4A: No information.
Database accession numbers
Revised June 25, 2008