|Molecule Type||Antigen Expression||Molecular Weight|
Min / Max
|Non-lineage Restricted Molecule|
|TSPAN3 is expressed in brain, colon, heart, kidney, liver, lung, pancreas, placenta, skeletal muscle, T cell and uterus.|
|MOLECULAR FAMILY NAME: Belong to the tetraspanin family.|
TSPAN3 is a multi-pass glycoprotein. TSPAN3 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of the members are cell surface proteins that are characterized by the presence of 4 hydrophobic domains. The use of alternate polyadenylation sites has been found for this gene.
Alternative splicing yields 2 different isoforms.
POST-TRANSLATIONAL MODIFICATION: No information.
LIGANDS AND MOLECULES ASSOCIATED WITH TSPAN3: No information.
TSPAN3 mediates signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TSPAN3 regulates the proliferation and migration of oligodendrocytes, a process essential for normal myelination and repair.
PROTEINS AND DNA ELEMENTS WHICH REGULATE TRANSCRIPTION OF TSPAN3: No information.
SUBSTRATES: No information.
ENZYMES WHICH MODIFY TSPAN3: No information.
Database accession numbers
Revised June 25, 2008